The University of Southampton
University of Southampton Institutional Repository

Stratified medicine for cancer therapy

Shaw, Emily C. and Johnson, Peter W. M. (2012) Stratified medicine for cancer therapy Drug Discovery Today, 17, (5-6), pp. 261-268. (doi:10.1016/j.drudis.2012.02.004). (PMID:22493785).

Record type: Article


As knowledge of the biological processes underlying malignant transformation becomes increasingly sophisticated, apparently similar diseases can be redefined according to the critical disrupted biological pathways and networks. The key genetic changes in most cancers can be mapped to one of a relatively few pathways, making it possible to classify tumours by their abnormal pathways and to identify potentially treatable--'druggable'--targets within these. The aim of the stratified approach to cancer therapy is to improve the effectiveness, tolerability and affordability of novel therapeutic agents.

Full text not available from this repository.

More information

Published date: March 2012
Organisations: Cancer Sciences


Local EPrints ID: 340835
ISSN: 1359-6446
PURE UUID: fd2010e9-d666-4fc4-87d0-b3d941bae224
ORCID for Peter W. M. Johnson: ORCID iD

Catalogue record

Date deposited: 03 Jul 2012 15:11
Last modified: 18 Jul 2017 05:41

Export record



Author: Emily C. Shaw

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton:

ePrints Soton supports OAI 2.0 with a base URL of

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.