Lim, Sean H. and Johnson, Peter W.M. (2011) Chemotherapy: advanced Hodgkin lymphoma - balancing toxicity and cure. Nature Reviews Clinical Oncology, 8 (11), 634-636. (doi:10.1038/nrclinonc.2011.137). (PMID:21894205)
Abstract
The combination of doxorubicin, bleomycin, vincristine and dacarbazine (ABVD) has emerged as a standard of care in advanced-stage Hodgkin lymphoma over the past four decades. Clinicians treating patients with cancer frequently walk a tightrope where the requirements of efficacy have to be balanced against the morbidity caused by the treatment.
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