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Documentation of functional and clinical effects of infant nutrition: setting the scene for COMMENT

Koletzko, B., Szajewska, H., Ashwell, M., Shamir, R., Aggett, P., Baerlocher, K, Noakes, P.S., Braegger, C., Calder, P.C., Campoy Folgoso, C., Colomb, V., Decsi, T., Domellöf, M., Dupont, C., Fewtrell, M., van Goudoever, J.B., Michaelsen, K.F., Mihatsch, W., Guarino, A., Koletzko, S., Rigo, J., Turck, D. and Taminiau, J. (2012) Documentation of functional and clinical effects of infant nutrition: setting the scene for COMMENT Annals of Nutrition and Metabolism, 60, (4), pp. 222-232. (doi:10.1159/000337681). (PMID:22677876).

Record type: Article

Abstract

The Early Nutrition Academy and the Child Health Foundation, in collaboration with the Committee on Nutrition, European Society for Paediatric Gastroenterology, Hepatology and Nutrition, held a workshop in March 2011 to explore guidance on acquiring evidence on the effects of nutritional interventions in infants and young children. The four objectives were to (1) provide guidance on the quality and quantity of evidence needed to justify conclusions on functional and clinical effects of nutrition in infants and young children aged <3 years; (2) agree on a range of outcome measures relevant to nutrition trials in this age group for which agreed criteria are needed; (3) agree on an updated ‘core data set’ that should generally be recorded in nutrition trials in infants and young children, and (4) provide guidance on the use of surrogate markers in paediatric nutrition research. The participants discussed these objectives and agreed to set up six first working groups under the auspices of the Consensus Group on Outcome Measures Made in Paediatric Enteral Nutrition Clinical Trials (COMMENT). Five groups will aim to identify and define criteria for assessing key outcomes, i.e. growth, acute diarrhoea, atopic dermatitis and cows’ milk protein allergy, infections and ‘gut comfort’. The sixth group will review and update the ‘core data set’. The COMMENT Steering Committee will discuss and decide upon a method for reaching consensus which will be used by all working groups and plan to meet again within 2 years and to report and publish their conclusions.

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More information

e-pub ahead of print date: 1 June 2012
Published date: June 2012
Organisations: Human Development & Health

Identifiers

Local EPrints ID: 341394
URI: http://eprints.soton.ac.uk/id/eprint/341394
ISSN: 0250-6807
PURE UUID: 42046772-1e7c-43e0-bd07-b10f3c083819

Catalogue record

Date deposited: 24 Jul 2012 10:23
Last modified: 18 Jul 2017 05:36

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Contributors

Author: B. Koletzko
Author: H. Szajewska
Author: M. Ashwell
Author: R. Shamir
Author: P. Aggett
Author: K Baerlocher
Author: P.S. Noakes
Author: C. Braegger
Author: P.C. Calder
Author: C. Campoy Folgoso
Author: V. Colomb
Author: T. Decsi
Author: M. Domellöf
Author: C. Dupont
Author: M. Fewtrell
Author: J.B. van Goudoever
Author: K.F. Michaelsen
Author: W. Mihatsch
Author: A. Guarino
Author: S. Koletzko
Author: J. Rigo
Author: D. Turck
Author: J. Taminiau

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