Media composition: amino acids and cellular homeostasis
Media composition: amino acids and cellular homeostasis
Amino acids are beneficial for the developing preimplantation embryo and therefore form an important component of culture media. This chapter will critically review the importance of amino acids for preimplantation embryos and the impact of this research for the development of sequential culture media used in many assisted conception units. The advantages of culturing embryos in a full complement of amino acids, at close to physiological concentrations will be considered. Moreover, the noninvasive measurement of amino acid turnover by individual embryos, a method which holds great promise to assess developmental competency prior to transfer, will also be discussed. Thus, this chapter highlights the fundamental role of amino acids for the metabolic and homeostatic regulation of the preimplantation embryo
978-1-61779-970-9
97-106
Houghton, Franchesca D.
53946041-127e-45a8-9edb-bf4b3c23005f
August 2012
Houghton, Franchesca D.
53946041-127e-45a8-9edb-bf4b3c23005f
Houghton, Franchesca D.
(2012)
Media composition: amino acids and cellular homeostasis.
In,
Embryo Culture Methods and Protocols.
(Methods in Molecular Biology, 912)
Humana Press, .
(doi:10.1007/978-1-61779-971-6_7).
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Abstract
Amino acids are beneficial for the developing preimplantation embryo and therefore form an important component of culture media. This chapter will critically review the importance of amino acids for preimplantation embryos and the impact of this research for the development of sequential culture media used in many assisted conception units. The advantages of culturing embryos in a full complement of amino acids, at close to physiological concentrations will be considered. Moreover, the noninvasive measurement of amino acid turnover by individual embryos, a method which holds great promise to assess developmental competency prior to transfer, will also be discussed. Thus, this chapter highlights the fundamental role of amino acids for the metabolic and homeostatic regulation of the preimplantation embryo
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Published date: August 2012
Organisations:
Human Development & Health
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Local EPrints ID: 341575
URI: http://eprints.soton.ac.uk/id/eprint/341575
ISBN: 978-1-61779-970-9
ISSN: 1064-3745
PURE UUID: 06139aaa-b2ee-41b7-bcd9-57e5705cfc0a
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Date deposited: 27 Jul 2012 14:11
Last modified: 15 Mar 2024 03:25
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