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Engineering virus functionalities on colloidal polyelectrolyte lipid composites

Engineering virus functionalities on colloidal polyelectrolyte lipid composites
Engineering virus functionalities on colloidal polyelectrolyte lipid composites
Polyelectrolyte-multilayered colloids were prepared employing the layer-by-layer technology. A lipid bilayer was then added, and finally rubella-like particles were fused. Immunofluorescence studies demonstrate that the colloidal biocomposites have a virus-like surface. Indeed, they were taken up into cells, while particles with an outer lipid layer were rarely found inside cells
1433-7851
2892-2895
Fischlechner, Martin
b3930129-0775-4c05-81c7-475934df97ee
Zschörnig, Olaf
a9068169-f2d6-4be4-bded-700215ebc5d2
Hofmann, Jörg
51c6970b-ef57-464c-bbfd-9d16ac12bfd3
Donath, Edwin
a1baee66-cc02-4a15-8c0d-732e844b8a8f
Fischlechner, Martin
b3930129-0775-4c05-81c7-475934df97ee
Zschörnig, Olaf
a9068169-f2d6-4be4-bded-700215ebc5d2
Hofmann, Jörg
51c6970b-ef57-464c-bbfd-9d16ac12bfd3
Donath, Edwin
a1baee66-cc02-4a15-8c0d-732e844b8a8f

Fischlechner, Martin, Zschörnig, Olaf, Hofmann, Jörg and Donath, Edwin (2005) Engineering virus functionalities on colloidal polyelectrolyte lipid composites. Angewandte Chemie International Edition, 44 (19), 2892-2895. (doi:10.1002/anie.200460763). (PMID:15827976)

Record type: Article

Abstract

Polyelectrolyte-multilayered colloids were prepared employing the layer-by-layer technology. A lipid bilayer was then added, and finally rubella-like particles were fused. Immunofluorescence studies demonstrate that the colloidal biocomposites have a virus-like surface. Indeed, they were taken up into cells, while particles with an outer lipid layer were rarely found inside cells

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e-pub ahead of print date: 13 April 2005
Published date: 6 May 2005
Organisations: Chemistry

Identifiers

Local EPrints ID: 342556
URI: http://eprints.soton.ac.uk/id/eprint/342556
ISSN: 1433-7851
PURE UUID: cc010b69-6bdc-43ab-b3d3-b2ea7bdb3976

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Date deposited: 12 Sep 2012 13:54
Last modified: 14 Mar 2024 11:52

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Contributors

Author: Martin Fischlechner
Author: Olaf Zschörnig
Author: Jörg Hofmann
Author: Edwin Donath

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