Danoux, Charlène, Tare, Rahul S., Smith, James, Bradley, Mark, Hunt, John A., Oreffo, Richard O.C. and Habibovic, Pamela
Development of materials for regenerative medicine: from clinical need to clinical application
de Boer, Jan and van Blitterswijk, Clemens (eds.)
Materiomics: High Throughput Screening of Biomaterial Properties.
Cambridge University Press
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Given the demographic challenges of an ageing population combined with rising patient expectation and the growing emphasis placed on cost containment by healthcare providers, economic regenerative medicine approaches for regeneration of damaged and diseased organs and tissues are a major clinical and socio-economic need. The scope of this chapter is to use skeletal regeneration as the exemplar to discuss classical and high-throughput screening approaches to biomaterials development for regenerative medicine, including choice and design of materials based on clinical need, biological assessment and regulatory issues
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