The University of Southampton
University of Southampton Institutional Repository

Adaptive responses of the embryo to maternal diet and consequences for post-implantation development

Fleming, Tom P., Lucas, Emma S., Watkins, Adam J. and Eckert, Judith J. (2011) Adaptive responses of the embryo to maternal diet and consequences for post-implantation development Reproduction, Fertility and Development, 24, (1), pp. 35-44. (doi:10.1071/RD11905). (PMID:22394716).

Record type: Article

Abstract

Maternal periconceptional (PC) nutrition, coupled with maternal physiological condition, can impact on reproductive performance and potential across mammalian species. Oocyte quality and embryo development are affected adversely by either nutrient restriction or excess. Moreover, the quality of maternal PC nutrition can have lasting effects through fetal development and postnatally into adulthood. Chronic disease, notably cardiovascular and metabolic disease, and abnormal behaviour have been identified in adult offspring in small and large animal models of PC nutrient restriction. These long-term effects associate with compensatory responses that begin from the time of early embryo development. This review assesses the field of PC nutrition in vivo on short- and long-term developmental consequences in rodent and ruminant models and considers the implications for human health.

Full text not available from this repository.

More information

Published date: 6 December 2011
Organisations: Biomedicine, Human Development & Health

Identifiers

Local EPrints ID: 343317
URI: http://eprints.soton.ac.uk/id/eprint/343317
ISSN: 1031-3613
PURE UUID: 73399400-ea97-4a20-aa02-11c29beda5f2

Catalogue record

Date deposited: 03 Oct 2012 10:38
Last modified: 18 Jul 2017 05:22

Export record

Altmetrics

Contributors

Author: Tom P. Fleming
Author: Emma S. Lucas
Author: Adam J. Watkins

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×