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Correlation between perceived asthma control and thoraco-abdominal asynchrony in primary care patients diagnosed with asthma

Correlation between perceived asthma control and thoraco-abdominal asynchrony in primary care patients diagnosed with asthma
Correlation between perceived asthma control and thoraco-abdominal asynchrony in primary care patients diagnosed with asthma
Objective. Thoraco-abdominal asynchrony (TAA), the discordant movement of the abdomen and thorax, may impact upon health-related variables. Here, we investigated the extent to which TAA is associated with health-related variables, particularly perceived asthma control and quality of life.
Methods. Ambulatory respiratory data from 43 patients diagnosed with asthma and 43 healthy age and sex-matched controls were recorded over 4 hours. Phase relation (Ph Rel Total), the percentage of time that the effects of rib cage (RC) and diaphragmatic movement result in opposite effects on intra-thoracic volume, quantified TAA. Subjects completed the Mini Asthma Quality of Life Questionnaire (AQLQ), Asthma Control Questionnaire (ACQ), Nijmegen questionnaire (NQ), Hospital Anxiety and Depression Scale (HADS), Spielberger State-Trait Anxiety Inventory (STAI), and General Health Perception (GHP) subscale of the short form 36 questionnaire. Capnography profiling, breath-hold time (BHT), and standard spirometry were performed.
Results. The time in asynchrony was significantly greater in the asthma than in the healthy control group (Ph Rel Total = 14% (interquartile range (IQR) 8.5–20.7%) versus 10.4% (IQR 7.1–14.5%), p = .012). In patients with asthma, Ph Rel Total was weakly associated with poorer ACQ scores (r = 0.33, p = .03), and in the healthy control group with GHP (r = 0.319, p = .037). Post-hoc exploratory analysis revealed a moderate relationship in the female asthma subgroup between Ph Rel Total and AQLQ (r = -0.56, p = .003).
Conclusions. TAA may be associated with decreased perceived asthma control. In healthy individuals, asynchrony may be associated with low perception of general health. Further studies are required to investigate if the reduction of TAA improves these health-related variables.
breathing training, perceived asthma control, respiratory pattern
0277-0903
822-9
Upton, Jane
c4b47f67-e068-475d-ac89-ef916bbdb3da
Brodie, David
4aa238f3-4884-431f-9bd1-ab86d4c801e5
Beales, David
c52890fb-cbf3-408b-a9a6-37bcf4f3cdc7
Richardson, Janet
0c0f4157-c4b3-4099-8fcf-00b63c604873
Jack, Sandy
3275b6b3-9f60-4901-9b2f-b03aab101638
Warburton, Chris
a699b502-3685-4e52-a722-a6f499a92f8f
Thomas, Mike
997c78e0-3849-4ce8-b1bc-86ebbdee3953
Kendrick, Adrian
f738a64d-4db6-4bd8-ba5a-7532003b5f3b
Upton, Jane
c4b47f67-e068-475d-ac89-ef916bbdb3da
Brodie, David
4aa238f3-4884-431f-9bd1-ab86d4c801e5
Beales, David
c52890fb-cbf3-408b-a9a6-37bcf4f3cdc7
Richardson, Janet
0c0f4157-c4b3-4099-8fcf-00b63c604873
Jack, Sandy
3275b6b3-9f60-4901-9b2f-b03aab101638
Warburton, Chris
a699b502-3685-4e52-a722-a6f499a92f8f
Thomas, Mike
997c78e0-3849-4ce8-b1bc-86ebbdee3953
Kendrick, Adrian
f738a64d-4db6-4bd8-ba5a-7532003b5f3b

Upton, Jane, Brodie, David, Beales, David, Richardson, Janet, Jack, Sandy, Warburton, Chris, Thomas, Mike and Kendrick, Adrian (2012) Correlation between perceived asthma control and thoraco-abdominal asynchrony in primary care patients diagnosed with asthma. Journal of Asthma, 49 (8), 822-9. (doi:10.3109/02770903.2012.717658). (PMID:22957811)

Record type: Article

Abstract

Objective. Thoraco-abdominal asynchrony (TAA), the discordant movement of the abdomen and thorax, may impact upon health-related variables. Here, we investigated the extent to which TAA is associated with health-related variables, particularly perceived asthma control and quality of life.
Methods. Ambulatory respiratory data from 43 patients diagnosed with asthma and 43 healthy age and sex-matched controls were recorded over 4 hours. Phase relation (Ph Rel Total), the percentage of time that the effects of rib cage (RC) and diaphragmatic movement result in opposite effects on intra-thoracic volume, quantified TAA. Subjects completed the Mini Asthma Quality of Life Questionnaire (AQLQ), Asthma Control Questionnaire (ACQ), Nijmegen questionnaire (NQ), Hospital Anxiety and Depression Scale (HADS), Spielberger State-Trait Anxiety Inventory (STAI), and General Health Perception (GHP) subscale of the short form 36 questionnaire. Capnography profiling, breath-hold time (BHT), and standard spirometry were performed.
Results. The time in asynchrony was significantly greater in the asthma than in the healthy control group (Ph Rel Total = 14% (interquartile range (IQR) 8.5–20.7%) versus 10.4% (IQR 7.1–14.5%), p = .012). In patients with asthma, Ph Rel Total was weakly associated with poorer ACQ scores (r = 0.33, p = .03), and in the healthy control group with GHP (r = 0.319, p = .037). Post-hoc exploratory analysis revealed a moderate relationship in the female asthma subgroup between Ph Rel Total and AQLQ (r = -0.56, p = .003).
Conclusions. TAA may be associated with decreased perceived asthma control. In healthy individuals, asynchrony may be associated with low perception of general health. Further studies are required to investigate if the reduction of TAA improves these health-related variables.

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More information

Published date: October 2012
Keywords: breathing training, perceived asthma control, respiratory pattern
Organisations: Primary Care & Population Sciences

Identifiers

Local EPrints ID: 343340
URI: http://eprints.soton.ac.uk/id/eprint/343340
ISSN: 0277-0903
PURE UUID: 658c1756-0e56-44c1-a722-406c7065613e

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Date deposited: 03 Oct 2012 11:14
Last modified: 08 Nov 2021 23:12

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Contributors

Author: Jane Upton
Author: David Brodie
Author: David Beales
Author: Janet Richardson
Author: Sandy Jack
Author: Chris Warburton
Author: Mike Thomas
Author: Adrian Kendrick

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