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Proximal interphalangeal joint replacement in patients with arthritis of the hand: a meta-analysis

Adams, J., Ryall, C., Pandyan, A., Metcalf, Cheryl, Stokes, M., Bradley, S. and Warwick, David J. (2012) Proximal interphalangeal joint replacement in patients with arthritis of the hand: a meta-analysis Journal of Bone and Joint Surgery, British Volume, 94-B, (10), 1305 -1312. (doi:10.1302/0301-620X.94B10.29035).

Record type: Article


We systematically reviewed all the evidence published in the English language on proximal interphalangeal joint (PIPJ) replacement, to determine its effectiveness on the function of the hand and the associated post-operative complications.

Original studies were selected if they reported clinical outcome with a minimum of one year’s follow-up. Quality was assessed using the Cowley systematic review criteria modified for finger-joint replacements. Of 319 articles identified, only five were adequately reported according to our quality criteria; there were no randomised controlled trials. PIPJ replacements had a substantial effect size on hand pain of -23.2 (95% confidence interval (CI) -27.3 to -19.1) and grip strength 1.2 (95% CI -10.7 to 13.1), and a small effect on range of movement 0.2 (95% CI -0.4 to 0.8). A dorsal approach was most successful. Post-operative loosening occurred in 10% (95% CI 3 to 30) of ceramic and 12.5% (95% CI 7 to 21) of pyrocarbon replacements. Post-operative complications occurred in 27.8% (95% CI 20 to 37).

We conclude that the effectiveness of PIPJ replacement has not been established. Small observational case studies and short-term follow-up, together with insufficient reporting of patient data, functional outcomes and complications, limit the value of current evidence.

We recommend that a defined core set of patients, surgical and outcome data for this intervention be routinely and systematically collected within the framework of a joint registry.

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Published date: September 2012
Organisations: Faculty of Health Sciences, Advancing Clinical & Expert Practice


Local EPrints ID: 343371
ISSN: 0021-9355
PURE UUID: 7fddd740-05eb-4586-8af1-aa4dca516ff3
ORCID for Cheryl Metcalf: ORCID iD
ORCID for M. Stokes: ORCID iD

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Date deposited: 03 Oct 2012 15:20
Last modified: 18 Jul 2017 05:22

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Author: J. Adams
Author: C. Ryall
Author: A. Pandyan
Author: Cheryl Metcalf ORCID iD
Author: M. Stokes ORCID iD
Author: S. Bradley
Author: David J. Warwick

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