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Multiscale modelling of lymphatic drainage

Multiscale modelling of lymphatic drainage
Multiscale modelling of lymphatic drainage
In this chapter we will describe the latest developments in the area of lymphatic modelling. The lymphatic system is one of the key elements of the human circulation, serving the dual functions of draining interstitial fluid and returning this to the general blood circulation, together with processing this lymph fluid which is a key component of the body’s immune response system. Compared to the main car- dovascular system however, remarkably little modelling has been attempted. At the same time, the distribution of pumping activity (contractile lymphangeons coupled with simple valves) throughout the system, passive primary lymphatics and com- plex lymph nodes combining to form an active network, makes the system a prime candidate for multiscale modelling
149-176
Springer
Roose, Tiina
3581ab5b-71e1-4897-8d88-59f13f3bccfe
Tabor, Gavin
156a9024-3b5f-4a94-9054-53555884f78c
Gefen, Amit
Roose, Tiina
3581ab5b-71e1-4897-8d88-59f13f3bccfe
Tabor, Gavin
156a9024-3b5f-4a94-9054-53555884f78c
Gefen, Amit

Roose, Tiina and Tabor, Gavin (2012) Multiscale modelling of lymphatic drainage. In, Gefen, Amit (ed.) Studies in Mechanobiology, Tissue Engineering and Biomaterials. New York, US. Springer, pp. 149-176. (In Press) (doi:10.1007/8415_2012_148).

Record type: Book Section

Abstract

In this chapter we will describe the latest developments in the area of lymphatic modelling. The lymphatic system is one of the key elements of the human circulation, serving the dual functions of draining interstitial fluid and returning this to the general blood circulation, together with processing this lymph fluid which is a key component of the body’s immune response system. Compared to the main car- dovascular system however, remarkably little modelling has been attempted. At the same time, the distribution of pumping activity (contractile lymphangeons coupled with simple valves) throughout the system, passive primary lymphatics and com- plex lymph nodes combining to form an active network, makes the system a prime candidate for multiscale modelling

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More information

Accepted/In Press date: 2012
Organisations: Bioengineering Group

Identifiers

Local EPrints ID: 344527
URI: https://eprints.soton.ac.uk/id/eprint/344527
PURE UUID: e18f3ce1-6854-415c-9252-2a770003f8a7
ORCID for Tiina Roose: ORCID iD orcid.org/0000-0001-8710-1063

Catalogue record

Date deposited: 25 Oct 2012 07:39
Last modified: 06 Jun 2018 12:36

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