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Urinary epidermal growth factor (hEGF) levels in patients with carcinomas of the breast, colon and rectum

Urinary epidermal growth factor (hEGF) levels in patients with carcinomas of the breast, colon and rectum
Urinary epidermal growth factor (hEGF) levels in patients with carcinomas of the breast, colon and rectum
A specific two-site ELISA for human epidermal growth factor (hEGF) has been used to measure urinary hEGF/creatinine ratios in 30 normal subjects, 30 hospital in-patients with breast cancer and 30 hospital in-patients with colonic or rectal cancer. There was no significant difference between patients with breast cancer and controls. Although a statistically significant difference between patients with colorectal cancer and controls was observed, the biological significance of this observation is doubtful. No clear effect of the presence of breast or colorectal carcinoma on the urinary excretion of hEGF has been observed.
0007-0920
459-461
Sweetenham, J.W.
4ea41ea4-f6aa-43c2-bb4c-804832d980e5
Davies, D.E.
7de8fdc7-3640-4e3a-aa91-d0e03f990c38
Warnes, S.
f724f4bf-86cf-4b7b-bf0a-69ba86e0185c
Alexander, P
bee35351-1f3a-4285-b781-ede69c5e0ec3
Sweetenham, J.W.
4ea41ea4-f6aa-43c2-bb4c-804832d980e5
Davies, D.E.
7de8fdc7-3640-4e3a-aa91-d0e03f990c38
Warnes, S.
f724f4bf-86cf-4b7b-bf0a-69ba86e0185c
Alexander, P
bee35351-1f3a-4285-b781-ede69c5e0ec3

Sweetenham, J.W., Davies, D.E., Warnes, S. and Alexander, P (1990) Urinary epidermal growth factor (hEGF) levels in patients with carcinomas of the breast, colon and rectum. British Journal of Cancer, 62 (3), 459-461. (doi:10.1038/bjc.1990.318). (PMID:2206955)

Record type: Article

Abstract

A specific two-site ELISA for human epidermal growth factor (hEGF) has been used to measure urinary hEGF/creatinine ratios in 30 normal subjects, 30 hospital in-patients with breast cancer and 30 hospital in-patients with colonic or rectal cancer. There was no significant difference between patients with breast cancer and controls. Although a statistically significant difference between patients with colorectal cancer and controls was observed, the biological significance of this observation is doubtful. No clear effect of the presence of breast or colorectal carcinoma on the urinary excretion of hEGF has been observed.

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Published date: September 1990
Organisations: Faculty of Medicine, Centre for Biological Sciences

Identifiers

Local EPrints ID: 344822
URI: https://eprints.soton.ac.uk/id/eprint/344822
ISSN: 0007-0920
PURE UUID: 88095744-a75f-4761-8db3-95622deaf511
ORCID for D.E. Davies: ORCID iD orcid.org/0000-0002-5117-2991

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Date deposited: 19 Feb 2013 17:02
Last modified: 24 May 2019 00:40

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