Triplex-directed covalent cross-linking of a DNA nanostructure


Rusling, David A., Nandhakumar, Iris S., Brown, Tom and Fox, Keith R. (2012) Triplex-directed covalent cross-linking of a DNA nanostructure Chemical Communications, 48, (77), pp. 9592-9594. (doi:10.1039/c2cc35407a).

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Description/Abstract

The triplex approach to DNA recognition is exploited to direct covalent inter-strand cross-links to unique locations within a pre-assembled DNA nanostructure. This approach can be used to improve the stability of DNA nanostructures and demonstrates the feasibility of directing other reactive groups to unique locations within these complexes.

Item Type: Article
Digital Object Identifier (DOI): doi:10.1039/c2cc35407a
ISSNs: 1359-7345 (print)
Subjects:
Organisations: Molecular and Cellular
ePrint ID: 345235
Date :
Date Event
10 August 2012Published
Date Deposited: 14 Nov 2012 12:07
Last Modified: 17 Apr 2017 16:22
Further Information:Google Scholar
URI: http://eprints.soton.ac.uk/id/eprint/345235

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