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Exome sequencing in tracking clonal evolution in multiple myeloma following therapy

Exome sequencing in tracking clonal evolution in multiple myeloma following therapy
Exome sequencing in tracking clonal evolution in multiple myeloma following therapy
Sequencing the tumor genome using next-generation sequencing (NGS) is providing an unparalleled insight into the pathogenesis and progression of the disease. Much of the current focus of NGS in cancer is on defining mutations in the tumor genome at disease presentation, and these findings are central to understanding the molecular mechanisms that underlie pathogenesis.
0887-6924
1188-1191
Weston-Bell, N.
c99c8c28-519f-4c3e-bd8c-679995a0472e
Gibson, J.
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John, M.
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Ennis, S.
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Pfeifer, S.
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Cezard, T.
df878ab5-11f4-4c7d-b897-8b1c9fa83ce7
Ludwig, H.
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Collins, Andrew
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Zojer, N.
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Sahota, S. S.
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Weston-Bell, N.
c99c8c28-519f-4c3e-bd8c-679995a0472e
Gibson, J.
855033a6-38f3-4853-8f60-d7d4561226ae
John, M.
99d82961-4c85-4568-8e11-b50946b0f2d3
Ennis, S.
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Pfeifer, S.
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Cezard, T.
df878ab5-11f4-4c7d-b897-8b1c9fa83ce7
Ludwig, H.
ff5c3f7b-d92f-411f-9e6a-53aa8fca4335
Collins, Andrew
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Zojer, N.
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Sahota, S. S.
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Weston-Bell, N., Gibson, J., John, M., Ennis, S., Pfeifer, S., Cezard, T., Ludwig, H., Collins, Andrew, Zojer, N. and Sahota, S. S. (2013) Exome sequencing in tracking clonal evolution in multiple myeloma following therapy. Leukemia, 27 (5), 1188-1191. (doi:10.1038/leu.2012.287). (PMID:23147253)

Record type: Article

Abstract

Sequencing the tumor genome using next-generation sequencing (NGS) is providing an unparalleled insight into the pathogenesis and progression of the disease. Much of the current focus of NGS in cancer is on defining mutations in the tumor genome at disease presentation, and these findings are central to understanding the molecular mechanisms that underlie pathogenesis.

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More information

e-pub ahead of print date: 9 October 2012
Published date: April 2013
Organisations: Cancer Sciences, Human Development & Health

Identifiers

Local EPrints ID: 345396
URI: http://eprints.soton.ac.uk/id/eprint/345396
ISSN: 0887-6924
PURE UUID: 78a1c498-49cc-41e9-b3ae-d4080e74475d
ORCID for N. Weston-Bell: ORCID iD orcid.org/0000-0003-0075-7276
ORCID for J. Gibson: ORCID iD orcid.org/0000-0002-0973-8285
ORCID for S. Ennis: ORCID iD orcid.org/0000-0003-2648-0869
ORCID for Andrew Collins: ORCID iD orcid.org/0000-0001-7108-0771

Catalogue record

Date deposited: 20 Nov 2012 11:27
Last modified: 15 Mar 2024 03:17

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Contributors

Author: N. Weston-Bell ORCID iD
Author: J. Gibson ORCID iD
Author: M. John
Author: S. Ennis ORCID iD
Author: S. Pfeifer
Author: T. Cezard
Author: H. Ludwig
Author: Andrew Collins ORCID iD
Author: N. Zojer
Author: S. S. Sahota

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