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Exome sequencing in tracking clonal evolution in multiple myeloma following therapy

Weston-Bell, N., Gibson, J., John, M., Ennis, S., Pfeifer, S., Cezard, T., Ludwig, H., Collins, Andrew, Zojer, N. and Sahota, S. S. (2013) Exome sequencing in tracking clonal evolution in multiple myeloma following therapy Leukemia, 27, (5), pp. 1188-1191. (doi:10.1038/leu.2012.287). (PMID:23147253).

Record type: Article

Abstract

Sequencing the tumor genome using next-generation sequencing (NGS) is providing an unparalleled insight into the pathogenesis and progression of the disease. Much of the current focus of NGS in cancer is on defining mutations in the tumor genome at disease presentation, and these findings are central to understanding the molecular mechanisms that underlie pathogenesis.

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e-pub ahead of print date: 9 October 2012
Published date: April 2013
Organisations: Cancer Sciences, Human Development & Health

Identifiers

Local EPrints ID: 345396
URI: http://eprints.soton.ac.uk/id/eprint/345396
ISSN: 0887-6924
PURE UUID: 78a1c498-49cc-41e9-b3ae-d4080e74475d
ORCID for J. Gibson: ORCID iD orcid.org/0000-0002-0973-8285
ORCID for Andrew Collins: ORCID iD orcid.org/0000-0001-7108-0771

Catalogue record

Date deposited: 20 Nov 2012 11:27
Last modified: 18 Jul 2017 05:10

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Contributors

Author: N. Weston-Bell
Author: J. Gibson ORCID iD
Author: M. John
Author: S. Ennis
Author: S. Pfeifer
Author: T. Cezard
Author: H. Ludwig
Author: Andrew Collins ORCID iD
Author: N. Zojer
Author: S. S. Sahota

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