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Small neutral molecular carriers for selective carboxylate transport

Small neutral molecular carriers for selective carboxylate transport
Small neutral molecular carriers for selective carboxylate transport
A series of neutral thiourea receptors were found to mediate the antiport of chloride with a range of biologically relevant carboxylate anions across phospholipid bilayers. Simple structural modification of the carriers resulted in a change in the lactate/pyruvate transport selectivity.



1359-7345
246-248
Haynes, Cally J. E.
c56ceaa2-ca95-4ef6-bcce-c5cb825c2ca0
Berry, Stuart N.
c7287fbf-5845-4f28-b3ab-bf3a35e3fd9f
Garric, Joachim
8683435f-46de-4a6a-ab1c-784a563bd30e
Herniman, Julie
530b1a36-1386-4602-8df7-defa6eb3512b
Hiscock, Jennifer R.
99a8a34c-a869-48e2-b713-1e69e4741032
Kirby, Isabelle L.
5839d488-f346-4741-b757-9ecf30777938
Light, Mark E.
cf57314e-6856-491b-a8d2-2dffc452e161
Perkes, Gregory
8615dadb-210a-4f3c-b407-97e7b9bcd90f
Gale, Philip A.
c840b7e9-6847-4843-91af-fa0f8563d943
Haynes, Cally J. E.
c56ceaa2-ca95-4ef6-bcce-c5cb825c2ca0
Berry, Stuart N.
c7287fbf-5845-4f28-b3ab-bf3a35e3fd9f
Garric, Joachim
8683435f-46de-4a6a-ab1c-784a563bd30e
Herniman, Julie
530b1a36-1386-4602-8df7-defa6eb3512b
Hiscock, Jennifer R.
99a8a34c-a869-48e2-b713-1e69e4741032
Kirby, Isabelle L.
5839d488-f346-4741-b757-9ecf30777938
Light, Mark E.
cf57314e-6856-491b-a8d2-2dffc452e161
Perkes, Gregory
8615dadb-210a-4f3c-b407-97e7b9bcd90f
Gale, Philip A.
c840b7e9-6847-4843-91af-fa0f8563d943

Haynes, Cally J. E., Berry, Stuart N., Garric, Joachim, Herniman, Julie, Hiscock, Jennifer R., Kirby, Isabelle L., Light, Mark E., Perkes, Gregory and Gale, Philip A. (2013) Small neutral molecular carriers for selective carboxylate transport. Chemical Communications, 49 (3), 246-248. (doi:10.1039/C2CC37468D).

Record type: Article

Abstract

A series of neutral thiourea receptors were found to mediate the antiport of chloride with a range of biologically relevant carboxylate anions across phospholipid bilayers. Simple structural modification of the carriers resulted in a change in the lactate/pyruvate transport selectivity.



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e-pub ahead of print date: 14 November 2012
Published date: 2013
Organisations: Organic Chemistry: Synthesis, Catalysis and Flow

Identifiers

Local EPrints ID: 345566
URI: http://eprints.soton.ac.uk/id/eprint/345566
DOI: doi:10.1039/C2CC37468D
ISSN: 1359-7345
PURE UUID: 3d506c52-b4c0-41aa-aa8b-6d854c83c4e5
ORCID for Julie Herniman: ORCID iD orcid.org/0000-0003-4834-1093
ORCID for Mark E. Light: ORCID iD orcid.org/0000-0002-0585-0843
ORCID for Philip A. Gale: ORCID iD orcid.org/0000-0001-9751-4910

Catalogue record

Date deposited: 26 Nov 2012 15:04
Last modified: 15 Mar 2024 03:06

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Contributors

Author: Cally J. E. Haynes
Author: Stuart N. Berry
Author: Joachim Garric
Author: Julie Herniman ORCID iD
Author: Jennifer R. Hiscock
Author: Isabelle L. Kirby
Author: Mark E. Light ORCID iD
Author: Gregory Perkes
Author: Philip A. Gale ORCID iD

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