Haynes, Cally J. E., Berry, Stuart N., Garric, Joachim, Herniman, Julie, Hiscock, Jennifer R., Kirby, Isabelle L., Light, Mark E., Perkes, Gregory and Gale, Philip A.
Small neutral molecular carriers for selective carboxylate transport
Chemical Communications, 49, (3), . (doi:10.1039/C2CC37468D).
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A series of neutral thiourea receptors were found to mediate the antiport of chloride with a range of biologically relevant carboxylate anions across phospholipid bilayers. Simple structural modification of the carriers resulted in a change in the lactate/pyruvate transport selectivity.
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