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Prediction of far-field acoustic emissions from cavitation clouds during shock wave lithotripsy for development of a clinical device

Prediction of far-field acoustic emissions from cavitation clouds during shock wave lithotripsy for development of a clinical device
Prediction of far-field acoustic emissions from cavitation clouds during shock wave lithotripsy for development of a clinical device
This study presents the key simulation and decision stage of a multi-disciplinary project to develop a hospital device for monitoring the effectiveness of kidney stone fragmentation by shock wave lithotripsy (SWL). The device analyses, in real time, the pressure fields detected by sensors placed on the patient's torso, fields generated by the interaction of the incident shock wave, cavitation, kidney stone and soft tissue. Earlier free-Lagrange simulations of those interactions were restricted (by limited computational resources) to computational domains within a few centimetres of the stone. Later studies estimated the far-field pressures generated when those interactions involved only single bubbles. This study extends the free-Lagrange method to quantify the bubble–bubble interaction as a function of their separation. This, in turn, allowed identification of the validity of using a model of non-interacting bubbles to obtain estimations of the far-field pressures from 1000 bubbles distributed within the focus of the SWL field. Up to this point in the multi-disciplinary project, the design of the clinical device had been led by the simulations. This study records the decision point when the project's direction had to be led by far more costly clinical trials instead of the relatively inexpensive simulations.

free-Lagrange simulations, shock–bubble interaction, acoustic emission, lithotripsy
1364-5021
20120538-[21pp]
Leighton, T. G.
3e5262ce-1d7d-42eb-b013-fcc5c286bbae
Turangan, C.K.
dad59b33-a4d7-4ac6-a49c-006e443e8ba4
Jamaluddin, A.R.
80faf5ed-1643-4c14-abaf-a1affcac9cf7
Ball, G.J.
2eb541a1-2a56-44c4-8ab1-4ff035fe87b7
White, P.R.
2dd2477b-5aa9-42e2-9d19-0806d994eaba
Leighton, T. G.
3e5262ce-1d7d-42eb-b013-fcc5c286bbae
Turangan, C.K.
dad59b33-a4d7-4ac6-a49c-006e443e8ba4
Jamaluddin, A.R.
80faf5ed-1643-4c14-abaf-a1affcac9cf7
Ball, G.J.
2eb541a1-2a56-44c4-8ab1-4ff035fe87b7
White, P.R.
2dd2477b-5aa9-42e2-9d19-0806d994eaba

Leighton, T. G., Turangan, C.K., Jamaluddin, A.R., Ball, G.J. and White, P.R. (2013) Prediction of far-field acoustic emissions from cavitation clouds during shock wave lithotripsy for development of a clinical device. Proceedings of the Royal Society A, 469 (2150), 20120538-[21pp]. (doi:10.1098/rspa.2012.0538).

Record type: Article

Abstract

This study presents the key simulation and decision stage of a multi-disciplinary project to develop a hospital device for monitoring the effectiveness of kidney stone fragmentation by shock wave lithotripsy (SWL). The device analyses, in real time, the pressure fields detected by sensors placed on the patient's torso, fields generated by the interaction of the incident shock wave, cavitation, kidney stone and soft tissue. Earlier free-Lagrange simulations of those interactions were restricted (by limited computational resources) to computational domains within a few centimetres of the stone. Later studies estimated the far-field pressures generated when those interactions involved only single bubbles. This study extends the free-Lagrange method to quantify the bubble–bubble interaction as a function of their separation. This, in turn, allowed identification of the validity of using a model of non-interacting bubbles to obtain estimations of the far-field pressures from 1000 bubbles distributed within the focus of the SWL field. Up to this point in the multi-disciplinary project, the design of the clinical device had been led by the simulations. This study records the decision point when the project's direction had to be led by far more costly clinical trials instead of the relatively inexpensive simulations.

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More information

e-pub ahead of print date: 12 December 2012
Published date: 8 February 2013
Keywords: free-Lagrange simulations, shock–bubble interaction, acoustic emission, lithotripsy
Organisations: Acoustics Group

Identifiers

Local EPrints ID: 346316
URI: http://eprints.soton.ac.uk/id/eprint/346316
ISSN: 1364-5021
PURE UUID: 71d308f3-ff94-4755-b60a-d39a984712f8
ORCID for T. G. Leighton: ORCID iD orcid.org/0000-0002-1649-8750
ORCID for P.R. White: ORCID iD orcid.org/0000-0002-4787-8713

Catalogue record

Date deposited: 17 Dec 2012 14:08
Last modified: 20 Jul 2019 01:25

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