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Nosocomial pandemic (H1N1) 2009, United Kingdom, 2009-2010

Nosocomial pandemic (H1N1) 2009, United Kingdom, 2009-2010
Nosocomial pandemic (H1N1) 2009, United Kingdom, 2009-2010
To determine clinical characteristics of patients hospitalized in the United Kingdom with pandemic (H1N1) 2009, we studied 1,520 patients in 75 National Health Service hospitals. We characterized patients who acquired influenza nosocomially during the pandemic (H1N1) 2009 outbreak. Of 30 patients, 12 (80%) of 15 adults and 14 (93%) of 15 children had serious underlying illnesses. Only 12 (57%) of 21 patients who received antiviral therapy did so within 48 hours after symptom onset, but 53% needed escalated care or mechanical ventilation; 8 (27%) of 30 died. Despite national guidelines and standardized infection control procedures, nosocomial transmission remains a problem when influenza is prevalent. Health care workers should be routinely offered influenza vaccine, and vaccination should be prioritized for all patients at high risk. Staff should remain alert to the possibility of influenza in patients with complex clinical problems and be ready to institute antiviral therapy while awaiting diagnosis during influenza outbreaks.
1080-6059
592-8
Enstone, Joanne E.
1e6488d9-b4ac-4c9c-9cd8-dd66e663752f
Myles, Puja R.
123c952c-b5b3-47bf-8e67-1d50bb40b114
Openshaw, Peter J.M.
43fb682a-04c9-4fc2-8404-674823f966a3
Gadd, Elaine M.
b4522ac1-8370-4a57-88de-5ada7ff03493
Lim, Wei Shen
89d4ce8c-fbc7-4f56-940e-e4c6533af05d
Semple, Malcolm G.
15b207df-e044-4078-9b40-1af17b800ab1
Read, Robert C.
b5caca7b-0063-438a-b703-7ecbb6fc2b51
Taylor, Bruce L.
c955af0e-2cfa-4a12-aadf-0178260e5b9d
McMenamin, James
d152729c-4145-4ee1-8fe2-838ae5f02604
Armstrong, Colin
69462aac-7500-45ad-9044-5bdb9fc4bbbd
Bannister, Barbara
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Nicholson, Karl G.
27948033-015f-4e4f-a8ed-1df896b42b0a
Nguyen-Van-Tam, Jonathan S.
1aac2164-f614-4c82-87f9-e123817bf128
Enstone, Joanne E.
1e6488d9-b4ac-4c9c-9cd8-dd66e663752f
Myles, Puja R.
123c952c-b5b3-47bf-8e67-1d50bb40b114
Openshaw, Peter J.M.
43fb682a-04c9-4fc2-8404-674823f966a3
Gadd, Elaine M.
b4522ac1-8370-4a57-88de-5ada7ff03493
Lim, Wei Shen
89d4ce8c-fbc7-4f56-940e-e4c6533af05d
Semple, Malcolm G.
15b207df-e044-4078-9b40-1af17b800ab1
Read, Robert C.
b5caca7b-0063-438a-b703-7ecbb6fc2b51
Taylor, Bruce L.
c955af0e-2cfa-4a12-aadf-0178260e5b9d
McMenamin, James
d152729c-4145-4ee1-8fe2-838ae5f02604
Armstrong, Colin
69462aac-7500-45ad-9044-5bdb9fc4bbbd
Bannister, Barbara
1e81bb1d-6896-4478-9b66-40081712072f
Nicholson, Karl G.
27948033-015f-4e4f-a8ed-1df896b42b0a
Nguyen-Van-Tam, Jonathan S.
1aac2164-f614-4c82-87f9-e123817bf128

Enstone, Joanne E., Myles, Puja R., Openshaw, Peter J.M., Gadd, Elaine M., Lim, Wei Shen, Semple, Malcolm G., Read, Robert C., Taylor, Bruce L., McMenamin, James, Armstrong, Colin, Bannister, Barbara, Nicholson, Karl G. and Nguyen-Van-Tam, Jonathan S. (2011) Nosocomial pandemic (H1N1) 2009, United Kingdom, 2009-2010. Emerging Infectious Diseases, 17 (4), 592-8. (doi:10.3201/eid1704.101679). (PMID:10493343)

Record type: Article

Abstract

To determine clinical characteristics of patients hospitalized in the United Kingdom with pandemic (H1N1) 2009, we studied 1,520 patients in 75 National Health Service hospitals. We characterized patients who acquired influenza nosocomially during the pandemic (H1N1) 2009 outbreak. Of 30 patients, 12 (80%) of 15 adults and 14 (93%) of 15 children had serious underlying illnesses. Only 12 (57%) of 21 patients who received antiviral therapy did so within 48 hours after symptom onset, but 53% needed escalated care or mechanical ventilation; 8 (27%) of 30 died. Despite national guidelines and standardized infection control procedures, nosocomial transmission remains a problem when influenza is prevalent. Health care workers should be routinely offered influenza vaccine, and vaccination should be prioritized for all patients at high risk. Staff should remain alert to the possibility of influenza in patients with complex clinical problems and be ready to institute antiviral therapy while awaiting diagnosis during influenza outbreaks.

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More information

Published date: April 2011
Organisations: Clinical & Experimental Sciences

Identifiers

Local EPrints ID: 346756
URI: http://eprints.soton.ac.uk/id/eprint/346756
ISSN: 1080-6059
PURE UUID: 966a4676-56cf-412f-bcd1-7f23ac2a2c17
ORCID for Robert C. Read: ORCID iD orcid.org/0000-0002-4297-6728

Catalogue record

Date deposited: 29 Jan 2013 10:04
Last modified: 15 Mar 2024 03:42

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Contributors

Author: Joanne E. Enstone
Author: Puja R. Myles
Author: Peter J.M. Openshaw
Author: Elaine M. Gadd
Author: Wei Shen Lim
Author: Malcolm G. Semple
Author: Robert C. Read ORCID iD
Author: Bruce L. Taylor
Author: James McMenamin
Author: Colin Armstrong
Author: Barbara Bannister
Author: Karl G. Nicholson
Author: Jonathan S. Nguyen-Van-Tam

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