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Perioperative buffered versus non-buffered fluid administration for surgery in adults

Burdett, Edward, Dushianthan, Ahilanandan, Bennett-Guerrero, Elliott, Cro, Suzie, Gan, Tong J., Grocott, Michael P.W., James, Michael F.M., Mythen, Michael G., O'Malley, Catherine M.N., Roche, Anthony M. and Rowan, Kathy (2012) Perioperative buffered versus non-buffered fluid administration for surgery in adults Cochrane Database of Systematic Reviews, 12, CD004089. (doi:10.1002/14651858.CD004089.pub2). (PMID:23235602).

Record type: Article


The administration of buffered fluids to adult patients during surgery is equally safe and effective as the administration of non-buffered saline-based fluids. The use of buffered fluids is associated with less metabolic derangement, in particular hyperchloraemia and metabolic acidosis. Larger studies are needed to assess robust outcomes such as mortality.

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Published date: December 2012
Organisations: Clinical & Experimental Sciences


Local EPrints ID: 347524
ISSN: 1469-493X
PURE UUID: 1cf7b1be-c9d1-4455-91ee-0107bf35ba39

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Date deposited: 23 Jan 2013 11:06
Last modified: 18 Jul 2017 04:57

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Author: Edward Burdett
Author: Ahilanandan Dushianthan
Author: Elliott Bennett-Guerrero
Author: Suzie Cro
Author: Tong J. Gan
Author: Michael F.M. James
Author: Michael G. Mythen
Author: Catherine M.N. O'Malley
Author: Anthony M. Roche
Author: Kathy Rowan

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