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Enantioselective organocatalytic synthesis of 5 and 6 membered heterocycles

Enantioselective organocatalytic synthesis of 5 and 6 membered heterocycles
Enantioselective organocatalytic synthesis of 5 and 6 membered heterocycles
During last decade the field of Organocatalysis emerged as one of the cornerstones of organic asymmetric synthesis. The use of organocatalysis has some advantages such as metal free reactions, environmentally friendly conditions, does not need to use dry solvents or inert atmosphere, avoid the use of protecting groups, etc … For these reasons, several research groups have focused their efforts on the development of new organocatalytic methodologies that render the final products in excellent yields and stereoselectivities. Concretely, the organocatalytic synthesis of 5 and 6 membered heterocycles has attracted much attention. In this review we have the aim to describe the different organocatalytic methodologies developed since in the synthesis of 5 and 6 heterocycles.
organocatalysis, michael reaction, 3+2 cycloaddition, diels-alder, domino reaction, heterocylic rings, organic chemistry, synthesis of azacycles, pyrrolidines, saturated heterocycles, nitrogen, addition-cyclization, 1, 3-dipolar cycloaddition, nitroaldehydes, homoproline derivatives
1385-2728
4046-4082
Vesely, Jan
1853ff19-a906-4321-bd69-f7e434176fc3
Rios, Ramon
609bedf2-e886-4d62-a676-a32b6f8c1441
Vesely, Jan
1853ff19-a906-4321-bd69-f7e434176fc3
Rios, Ramon
609bedf2-e886-4d62-a676-a32b6f8c1441

Vesely, Jan and Rios, Ramon (2011) Enantioselective organocatalytic synthesis of 5 and 6 membered heterocycles. Current Organic Chemistry, 15 (24), 4046-4082. (doi:10.2174/138527211798109213).

Record type: Article

Abstract

During last decade the field of Organocatalysis emerged as one of the cornerstones of organic asymmetric synthesis. The use of organocatalysis has some advantages such as metal free reactions, environmentally friendly conditions, does not need to use dry solvents or inert atmosphere, avoid the use of protecting groups, etc … For these reasons, several research groups have focused their efforts on the development of new organocatalytic methodologies that render the final products in excellent yields and stereoselectivities. Concretely, the organocatalytic synthesis of 5 and 6 membered heterocycles has attracted much attention. In this review we have the aim to describe the different organocatalytic methodologies developed since in the synthesis of 5 and 6 heterocycles.

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More information

Published date: 2011
Keywords: organocatalysis, michael reaction, 3+2 cycloaddition, diels-alder, domino reaction, heterocylic rings, organic chemistry, synthesis of azacycles, pyrrolidines, saturated heterocycles, nitrogen, addition-cyclization, 1, 3-dipolar cycloaddition, nitroaldehydes, homoproline derivatives
Organisations: Chemistry

Identifiers

Local EPrints ID: 347695
URI: http://eprints.soton.ac.uk/id/eprint/347695
ISSN: 1385-2728
PURE UUID: 3f8e1e46-3360-423c-899d-9968ddce81c9
ORCID for Ramon Rios: ORCID iD orcid.org/0000-0002-3843-8521

Catalogue record

Date deposited: 29 Jan 2013 11:11
Last modified: 14 Mar 2024 12:51

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Contributors

Author: Jan Vesely
Author: Ramon Rios ORCID iD

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