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One-pot, three-component, highly diastereoselective metal-free synthesis of 2,3,4,5-tetrasubstituted pyrrolidines

One-pot, three-component, highly diastereoselective metal-free synthesis of 2,3,4,5-tetrasubstituted pyrrolidines
One-pot, three-component, highly diastereoselective metal-free synthesis of 2,3,4,5-tetrasubstituted pyrrolidines
An extremely efficient, highly diastereoselective, metal-free synthesis of 2,3,4,5-tetrasubstituted pyrrolidines is described. The three-component reaction between aldehydes, aminomalonates, and nitroalkenes proceeds with high diastereoselectivities and high yields.
metal-free, cycloaddition, three component, pyrrolidines, stereoselectivity
0936-5214
1840-1844
Rios, Ramon
609bedf2-e886-4d62-a676-a32b6f8c1441
Crovetto, Luis
45d4cd97-3fe5-4498-a861-bc06492eb09d
Rios, Ramon
609bedf2-e886-4d62-a676-a32b6f8c1441
Crovetto, Luis
45d4cd97-3fe5-4498-a861-bc06492eb09d

Rios, Ramon and Crovetto, Luis (2008) One-pot, three-component, highly diastereoselective metal-free synthesis of 2,3,4,5-tetrasubstituted pyrrolidines. Synlett, 2008 (12), 1840-1844. (doi:10.1055/s-2008-1078566).

Record type: Article

Abstract

An extremely efficient, highly diastereoselective, metal-free synthesis of 2,3,4,5-tetrasubstituted pyrrolidines is described. The three-component reaction between aldehydes, aminomalonates, and nitroalkenes proceeds with high diastereoselectivities and high yields.

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More information

Published date: 2008
Keywords: metal-free, cycloaddition, three component, pyrrolidines, stereoselectivity
Organisations: Chemistry

Identifiers

Local EPrints ID: 347735
URI: http://eprints.soton.ac.uk/id/eprint/347735
ISSN: 0936-5214
PURE UUID: 532dbf7c-47fb-4329-ae01-f3cd5710eba9
ORCID for Ramon Rios: ORCID iD orcid.org/0000-0002-3843-8521

Catalogue record

Date deposited: 29 Jan 2013 13:56
Last modified: 10 Dec 2019 01:37

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