Highly enantioselective synthesis of 2H-1-benzothiopyrans by a catalytic domino reaction
Highly enantioselective synthesis of 2H-1-benzothiopyrans by a catalytic domino reaction
A highly enantioselective catalytic asymmetric synthesis of 2H-1-benzothiopyrans is presented. The organocatalytic asymmetric domino reactions between 2-mercaptobenzaldehyde and ?,?-unsaturated aldehydes proceed with excellent chemo- and enantioselectivities to give the corresponding pharmaceutically valuable benzothiopyrans in high yields with 91–98% ee.
8547-8551
Rios, Ramon
609bedf2-e886-4d62-a676-a32b6f8c1441
Sundén, Henrik
fe114b08-1de1-4e88-9778-a9cddf3aa76d
Ibrahem, Ismail
3cbac9c1-431b-4a1f-8c41-92aa617254b0
Zhao, Gui-Ling
106737c0-2aeb-4805-a8d7-496b1ce04322
Eriksson, Lars
340ffb17-9c8e-468f-acba-13219dc22c37
Córdova, Armando
d2a1239f-708d-4f9c-bf7c-c095e9a27cac
27 November 2006
Rios, Ramon
609bedf2-e886-4d62-a676-a32b6f8c1441
Sundén, Henrik
fe114b08-1de1-4e88-9778-a9cddf3aa76d
Ibrahem, Ismail
3cbac9c1-431b-4a1f-8c41-92aa617254b0
Zhao, Gui-Ling
106737c0-2aeb-4805-a8d7-496b1ce04322
Eriksson, Lars
340ffb17-9c8e-468f-acba-13219dc22c37
Córdova, Armando
d2a1239f-708d-4f9c-bf7c-c095e9a27cac
Rios, Ramon, Sundén, Henrik, Ibrahem, Ismail, Zhao, Gui-Ling, Eriksson, Lars and Córdova, Armando
(2006)
Highly enantioselective synthesis of 2H-1-benzothiopyrans by a catalytic domino reaction.
Tetrahedron Letters, 47 (48), .
(doi:10.1016/j.tetlet.2006.09.135).
Abstract
A highly enantioselective catalytic asymmetric synthesis of 2H-1-benzothiopyrans is presented. The organocatalytic asymmetric domino reactions between 2-mercaptobenzaldehyde and ?,?-unsaturated aldehydes proceed with excellent chemo- and enantioselectivities to give the corresponding pharmaceutically valuable benzothiopyrans in high yields with 91–98% ee.
This record has no associated files available for download.
More information
Published date: 27 November 2006
Organisations:
Chemistry
Identifiers
Local EPrints ID: 347972
URI: http://eprints.soton.ac.uk/id/eprint/347972
ISSN: 0040-4039
PURE UUID: 0745fa69-6089-4c2d-abd9-da3d452a27e6
Catalogue record
Date deposited: 05 Feb 2013 09:37
Last modified: 14 Mar 2024 12:54
Export record
Altmetrics
Contributors
Author:
Henrik Sundén
Author:
Ismail Ibrahem
Author:
Gui-Ling Zhao
Author:
Lars Eriksson
Author:
Armando Córdova
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics
