The University of Southampton
University of Southampton Institutional Repository

A simple organocatalytic enantioselective cyclopropanation of ?,?-unsaturated aldehydes

A simple organocatalytic enantioselective cyclopropanation of ?,?-unsaturated aldehydes
A simple organocatalytic enantioselective cyclopropanation of ?,?-unsaturated aldehydes
A highly chemo- and enantioselective organocatalytic cyclopropanation of ?,?-unsaturated aldehydes with bromomalonate and 2-bromoacetoacetate esters is presented. The reaction is catalyzed by chiral amines and gives access to 2-formylcyclopropanes in high yields and up to 99?% ee.
asymmetric catalysis, cyclopropanes, domino reactions, halomalonates, organocatalysis, ?, ?-unsaturated aldehydes
1615-4150
1028-1032
Rios, Ramon
609bedf2-e886-4d62-a676-a32b6f8c1441
Sundén, Henrik
fe114b08-1de1-4e88-9778-a9cddf3aa76d
Vesely, Jan
1853ff19-a906-4321-bd69-f7e434176fc3
Zhao, Gui-Ling
106737c0-2aeb-4805-a8d7-496b1ce04322
Dziedzic, Pawel
f1a3d742-6349-4e42-82c5-98f005aab0f7
Córdova, Armando
d2a1239f-708d-4f9c-bf7c-c095e9a27cac
Rios, Ramon
609bedf2-e886-4d62-a676-a32b6f8c1441
Sundén, Henrik
fe114b08-1de1-4e88-9778-a9cddf3aa76d
Vesely, Jan
1853ff19-a906-4321-bd69-f7e434176fc3
Zhao, Gui-Ling
106737c0-2aeb-4805-a8d7-496b1ce04322
Dziedzic, Pawel
f1a3d742-6349-4e42-82c5-98f005aab0f7
Córdova, Armando
d2a1239f-708d-4f9c-bf7c-c095e9a27cac

Rios, Ramon, Sundén, Henrik, Vesely, Jan, Zhao, Gui-Ling, Dziedzic, Pawel and Córdova, Armando (2007) A simple organocatalytic enantioselective cyclopropanation of ?,?-unsaturated aldehydes. Advanced Synthesis & Catalysis, 349 (7), 1028-1032. (doi:10.1002/adsc.200700032).

Record type: Article

Abstract

A highly chemo- and enantioselective organocatalytic cyclopropanation of ?,?-unsaturated aldehydes with bromomalonate and 2-bromoacetoacetate esters is presented. The reaction is catalyzed by chiral amines and gives access to 2-formylcyclopropanes in high yields and up to 99?% ee.

Full text not available from this repository.

More information

Published date: 7 May 2007
Keywords: asymmetric catalysis, cyclopropanes, domino reactions, halomalonates, organocatalysis, ?, ?-unsaturated aldehydes
Organisations: Chemistry

Identifiers

Local EPrints ID: 347975
URI: http://eprints.soton.ac.uk/id/eprint/347975
ISSN: 1615-4150
PURE UUID: 01feb364-188b-4ca8-a34a-30e9ce51a44f
ORCID for Ramon Rios: ORCID iD orcid.org/0000-0002-3843-8521

Catalogue record

Date deposited: 05 Feb 2013 09:49
Last modified: 10 Dec 2019 01:37

Export record

Altmetrics

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×