Asymmetric amplification in the amino acid-catalyzed synthesis of amino acid derivatives
Asymmetric amplification in the amino acid-catalyzed synthesis of amino acid derivatives
The origins of biological homochirality have intrigued researchers since Pasteur’s discovery of the optical activity of biomolecules. Herein, we present the first example of asymmetric amplification in the amino acid-catalyzed enantioselective synthesis of amino acid derivatives that provides support for a synergistic model for the evolution of homochirality by amino acid catalysis.
amino acids, asymmetric amplification, homochirality, kinetic resolution
1868-1872
Ibrahem, Ismail
3cbac9c1-431b-4a1f-8c41-92aa617254b0
Sundén, Henrik
fe114b08-1de1-4e88-9778-a9cddf3aa76d
Dziedzic, Pawel
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Rios, Ramon
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Córdova, Armando
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6 August 2007
Ibrahem, Ismail
3cbac9c1-431b-4a1f-8c41-92aa617254b0
Sundén, Henrik
fe114b08-1de1-4e88-9778-a9cddf3aa76d
Dziedzic, Pawel
f1a3d742-6349-4e42-82c5-98f005aab0f7
Rios, Ramon
609bedf2-e886-4d62-a676-a32b6f8c1441
Córdova, Armando
d2a1239f-708d-4f9c-bf7c-c095e9a27cac
Ibrahem, Ismail, Sundén, Henrik, Dziedzic, Pawel, Rios, Ramon and Córdova, Armando
(2007)
Asymmetric amplification in the amino acid-catalyzed synthesis of amino acid derivatives.
Advanced Synthesis & Catalysis, 349 (11-12), .
(doi:10.1002/adsc.200700110).
Abstract
The origins of biological homochirality have intrigued researchers since Pasteur’s discovery of the optical activity of biomolecules. Herein, we present the first example of asymmetric amplification in the amino acid-catalyzed enantioselective synthesis of amino acid derivatives that provides support for a synergistic model for the evolution of homochirality by amino acid catalysis.
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Published date: 6 August 2007
Keywords:
amino acids, asymmetric amplification, homochirality, kinetic resolution
Organisations:
Chemistry
Identifiers
Local EPrints ID: 347980
URI: http://eprints.soton.ac.uk/id/eprint/347980
ISSN: 1615-4150
PURE UUID: 3af12e42-e118-4e02-9e3e-f911d0910442
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Date deposited: 05 Feb 2013 10:06
Last modified: 14 Mar 2024 12:54
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Contributors
Author:
Ismail Ibrahem
Author:
Henrik Sundén
Author:
Pawel Dziedzic
Author:
Armando Córdova
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