Examples of catalytic asymmetric amine synthesis using organic catalysts
Examples of catalytic asymmetric amine synthesis using organic catalysts
The asymmetric construction of optically active amine compounds is of paramount interest for the chemical industry and academic research. This review describes the use of catalytic asymmetric transformations, such as Mannich-type, Michael, cycloaddition and transfer-hydrogenation reactions using small organic molecules (eg, amino acids, secondary amines, peptides, thioureas and phosphoric acids) as catalysts, for the construction of important compounds for medicinal chemistry that exhibit anticancer, antibiotic or antiviral activity.
824-847
Rios, R.
609bedf2-e886-4d62-a676-a32b6f8c1441
Córdova, A.
8e10913c-2f20-4fa3-99dd-73c0c51a16e8
November 2009
Rios, R.
609bedf2-e886-4d62-a676-a32b6f8c1441
Córdova, A.
8e10913c-2f20-4fa3-99dd-73c0c51a16e8
Rios, R. and Córdova, A.
(2009)
Examples of catalytic asymmetric amine synthesis using organic catalysts.
Current Opinion in Drug Discovery & Development, 12 (6), .
(PMID:19894193)
Abstract
The asymmetric construction of optically active amine compounds is of paramount interest for the chemical industry and academic research. This review describes the use of catalytic asymmetric transformations, such as Mannich-type, Michael, cycloaddition and transfer-hydrogenation reactions using small organic molecules (eg, amino acids, secondary amines, peptides, thioureas and phosphoric acids) as catalysts, for the construction of important compounds for medicinal chemistry that exhibit anticancer, antibiotic or antiviral activity.
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Published date: November 2009
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Chemistry
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Local EPrints ID: 348007
URI: http://eprints.soton.ac.uk/id/eprint/348007
ISSN: 1367-6733
PURE UUID: 8cd16fe9-45d3-429f-bbb4-e337d18daf67
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Date deposited: 05 Feb 2013 11:48
Last modified: 08 Jan 2022 03:16
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Author:
A. Córdova
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