The University of Southampton
University of Southampton Institutional Repository

Examples of catalytic asymmetric amine synthesis using organic catalysts

Examples of catalytic asymmetric amine synthesis using organic catalysts
Examples of catalytic asymmetric amine synthesis using organic catalysts
The asymmetric construction of optically active amine compounds is of paramount interest for the chemical industry and academic research. This review describes the use of catalytic asymmetric transformations, such as Mannich-type, Michael, cycloaddition and transfer-hydrogenation reactions using small organic molecules (eg, amino acids, secondary amines, peptides, thioureas and phosphoric acids) as catalysts, for the construction of important compounds for medicinal chemistry that exhibit anticancer, antibiotic or antiviral activity.
1367-6733
824-847
Rios, R.
609bedf2-e886-4d62-a676-a32b6f8c1441
Córdova, A.
8e10913c-2f20-4fa3-99dd-73c0c51a16e8
Rios, R.
609bedf2-e886-4d62-a676-a32b6f8c1441
Córdova, A.
8e10913c-2f20-4fa3-99dd-73c0c51a16e8

Rios, R. and Córdova, A. (2009) Examples of catalytic asymmetric amine synthesis using organic catalysts. Current Opinion in Drug Discovery & Development, 12 (6), 824-847. (PMID:19894193)

Record type: Article

Abstract

The asymmetric construction of optically active amine compounds is of paramount interest for the chemical industry and academic research. This review describes the use of catalytic asymmetric transformations, such as Mannich-type, Michael, cycloaddition and transfer-hydrogenation reactions using small organic molecules (eg, amino acids, secondary amines, peptides, thioureas and phosphoric acids) as catalysts, for the construction of important compounds for medicinal chemistry that exhibit anticancer, antibiotic or antiviral activity.

This record has no associated files available for download.

More information

Published date: November 2009
Organisations: Chemistry

Identifiers

Local EPrints ID: 348007
URI: http://eprints.soton.ac.uk/id/eprint/348007
ISSN: 1367-6733
PURE UUID: 8cd16fe9-45d3-429f-bbb4-e337d18daf67
ORCID for R. Rios: ORCID iD orcid.org/0000-0002-3843-8521

Catalogue record

Date deposited: 05 Feb 2013 11:48
Last modified: 08 Jan 2022 03:16

Export record

Contributors

Author: R. Rios ORCID iD
Author: A. Córdova

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×