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Nasal self-swabbing for estimating the prevalence of Staphylococcus aureus in the community

Nasal self-swabbing for estimating the prevalence of Staphylococcus aureus in the community
Nasal self-swabbing for estimating the prevalence of Staphylococcus aureus in the community
Staphylococcus aureus remains a significant cause of morbidity and mortality and therefore a burden on healthcare systems. Our aim was to estimate the current rate of nasal S. aureus carriage in the general population and to determine the feasibility of nasal self-swabbing. Two thousand people (1200 adults and 800 children) from a single NHS general practice in Southampton UK were randomly selected from a GP age sex register, stratified by age and sex, and invited to undertake nasal self-swabbing in their own home. Overall, 362 (32.5%) adult and 168 (22%) child swabs were returned. Responses were greater for adults, increased age, female gender and decreasing socio-economic deprivation. The overall estimated practice carriage rate of S. aureus directly standardised for age sex was 28% (95% CI 26.1% to 30.2%). Carriage of meticillin-susceptible S. aureus was 27% (95% CI 26.1% to 30.2%) whilst that of meticillin resistant S. aureus was 1.9% (95% CI 0.7% to 3.1%). Although nasal self-swabbing rates were relatively low, they are comparable to other studies and may allow large population-based carriage studies to be undertaken at relatively low cost. Importantly, this study updates prevalence data for S. aureus carriage in the community.
0022-2615
437-440
Gamblin, J.
b1761a23-4ad6-4a61-9dbd-6f93ded89f31
Jefferies, Johanna M.C.
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Harris, S.
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Ahmad, N.
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Marsh, P.
28ca4a02-c63e-45bb-8288-52806daad572
Faust, S.N.
f97df780-9f9b-418e-b349-7adf63e150c1
Fraser, S.
135884b6-8737-4e8a-a98c-5d803ac7a2dc
Moore, Michael
1be81dad-7120-45f0-bbed-f3b0cc0cfe99
Roderick, Paul
dbb3cd11-4c51-4844-982b-0eb30ad5085a
Blair, I.
82f13b66-00fd-4275-bad0-2ec5694e943b
Clarke, Stuart C.
f7d7f7a2-4b1f-4b36-883a-0f967e73fb17
Gamblin, J.
b1761a23-4ad6-4a61-9dbd-6f93ded89f31
Jefferies, Johanna M.C.
9468e292-0b41-412d-9470-944e257c7bcf
Harris, S.
19ea097b-df15-4f0f-be19-8ac42c190028
Ahmad, N.
d2ca1654-dcdf-4508-ac20-c1912fe44785
Marsh, P.
28ca4a02-c63e-45bb-8288-52806daad572
Faust, S.N.
f97df780-9f9b-418e-b349-7adf63e150c1
Fraser, S.
135884b6-8737-4e8a-a98c-5d803ac7a2dc
Moore, Michael
1be81dad-7120-45f0-bbed-f3b0cc0cfe99
Roderick, Paul
dbb3cd11-4c51-4844-982b-0eb30ad5085a
Blair, I.
82f13b66-00fd-4275-bad0-2ec5694e943b
Clarke, Stuart C.
f7d7f7a2-4b1f-4b36-883a-0f967e73fb17

Gamblin, J., Jefferies, Johanna M.C., Harris, S., Ahmad, N., Marsh, P., Faust, S.N., Fraser, S., Moore, Michael, Roderick, Paul, Blair, I. and Clarke, Stuart C. (2013) Nasal self-swabbing for estimating the prevalence of Staphylococcus aureus in the community. Journal of Medical Microbiology, 62 (Pt 3), 437-440. (doi:10.1099/jmm.0.051854-0). (PMID:23222858)

Record type: Article

Abstract

Staphylococcus aureus remains a significant cause of morbidity and mortality and therefore a burden on healthcare systems. Our aim was to estimate the current rate of nasal S. aureus carriage in the general population and to determine the feasibility of nasal self-swabbing. Two thousand people (1200 adults and 800 children) from a single NHS general practice in Southampton UK were randomly selected from a GP age sex register, stratified by age and sex, and invited to undertake nasal self-swabbing in their own home. Overall, 362 (32.5%) adult and 168 (22%) child swabs were returned. Responses were greater for adults, increased age, female gender and decreasing socio-economic deprivation. The overall estimated practice carriage rate of S. aureus directly standardised for age sex was 28% (95% CI 26.1% to 30.2%). Carriage of meticillin-susceptible S. aureus was 27% (95% CI 26.1% to 30.2%) whilst that of meticillin resistant S. aureus was 1.9% (95% CI 0.7% to 3.1%). Although nasal self-swabbing rates were relatively low, they are comparable to other studies and may allow large population-based carriage studies to be undertaken at relatively low cost. Importantly, this study updates prevalence data for S. aureus carriage in the community.

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Published date: March 2013
Organisations: Faculty of Medicine, Primary Care & Population Sciences

Identifiers

Local EPrints ID: 348142
URI: https://eprints.soton.ac.uk/id/eprint/348142
ISSN: 0022-2615
PURE UUID: d06e47fb-9137-4152-805d-181ba88cb11c
ORCID for S.N. Faust: ORCID iD orcid.org/0000-0003-3410-7642
ORCID for S. Fraser: ORCID iD orcid.org/0000-0002-4172-4406
ORCID for Michael Moore: ORCID iD orcid.org/0000-0002-5127-4509
ORCID for Paul Roderick: ORCID iD orcid.org/0000-0001-9475-6850
ORCID for Stuart C. Clarke: ORCID iD orcid.org/0000-0002-7009-1548

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Date deposited: 07 Feb 2013 12:52
Last modified: 01 Oct 2019 01:00

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