Prenatal and nutritional influences on skeletal development: lessons from animal studies
Prenatal and nutritional influences on skeletal development: lessons from animal studies
It is now well established that the onset of adult diseases such as heart disease, stroke, type 2 diabetes and hypertension are linked to an adverse uterine growth environment, in particular through maternal nutrition, during development of the individual. The geographical distribution of the incidence rate of heart disease is similar to that of osteoporosis. This may indicate a link between maternal nutrition during pregnancy and the subsequent risk of developing osteoporosis in the offspring. This review summarises what we know to date, from animal models, about maternal nutrition and the subsequent alterations in the offspring’s skeletal structure.
40-48
Lanham, S.A.
28fdbbef-e3b6-4fdf-bd0f-4968eeb614d6
Roach, Helmtrud I.
ca2ff1f4-1ada-4c56-9097-cd27ca4d199e
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Oreffo, Richard O.C.
ff9fff72-6855-4d0f-bfb2-311d0e8f3778
March 2010
Lanham, S.A.
28fdbbef-e3b6-4fdf-bd0f-4968eeb614d6
Roach, Helmtrud I.
ca2ff1f4-1ada-4c56-9097-cd27ca4d199e
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Oreffo, Richard O.C.
ff9fff72-6855-4d0f-bfb2-311d0e8f3778
Lanham, S.A., Roach, Helmtrud I., Cooper, Cyrus and Oreffo, Richard O.C.
(2010)
Prenatal and nutritional influences on skeletal development: lessons from animal studies.
Clinical Reviews in Bone and Mineral Metabolism, 8 (1), .
(doi:10.1007/s12018-009-9065-3).
Abstract
It is now well established that the onset of adult diseases such as heart disease, stroke, type 2 diabetes and hypertension are linked to an adverse uterine growth environment, in particular through maternal nutrition, during development of the individual. The geographical distribution of the incidence rate of heart disease is similar to that of osteoporosis. This may indicate a link between maternal nutrition during pregnancy and the subsequent risk of developing osteoporosis in the offspring. This review summarises what we know to date, from animal models, about maternal nutrition and the subsequent alterations in the offspring’s skeletal structure.
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Published date: March 2010
Organisations:
Human Development & Health
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Local EPrints ID: 348227
URI: http://eprints.soton.ac.uk/id/eprint/348227
ISSN: 1534-8644
PURE UUID: 8180658c-bc01-4f33-b70f-0115719c6b0c
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Date deposited: 08 Feb 2013 16:39
Last modified: 18 Mar 2024 02:51
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Author:
S.A. Lanham
Author:
Helmtrud I. Roach
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