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Caudwell Xtreme Everest: a field study of human adaptation to hypoxia

Caudwell Xtreme Everest: a field study of human adaptation to hypoxia
Caudwell Xtreme Everest: a field study of human adaptation to hypoxia
Caudwell Xtreme Everest (CXE) is a large healthy volunteer field study investigating human adaptation to environmental hypoxia. More than 200 individuals were studied at sea-level and in four laboratories on the trek to Everest Base Camp (5,300 m). Fifteen physicians climbed high on Everest and continued the studies as they ascended; eight of these individuals reached the summit of Everest and succeeded in sampling arterial blood at 8,400 m on their descent. Core measurements included cardiopulmonary exercise testing, neuropsychological assessment, near infra-red spectroscopy of brain and exercising muscle, blood markers and daily recording of simple physiological variables. The goal of CXE is to further our understanding of human adaptation to cellular hypoxia, a fundamental mechanism of injury in critical illness, with the aim of improving the care of critically ill patients.
1364-8535
151-152
Grocott, Mike
1e87b741-513e-4a22-be13-0f7bb344e8c2
Richardson, Alan
d26396c7-3342-4f4b-82d0-6a8f0d62059b
Montgomery, Hugh
ec760637-aea7-43be-98d1-71a1f72e6efa
Mythen, Monty
ced4210c-1c97-4e00-aa51-58dea2959848
Grocott, Mike
1e87b741-513e-4a22-be13-0f7bb344e8c2
Richardson, Alan
d26396c7-3342-4f4b-82d0-6a8f0d62059b
Montgomery, Hugh
ec760637-aea7-43be-98d1-71a1f72e6efa
Mythen, Monty
ced4210c-1c97-4e00-aa51-58dea2959848

Grocott, Mike, Richardson, Alan, Montgomery, Hugh and Mythen, Monty (2007) Caudwell Xtreme Everest: a field study of human adaptation to hypoxia Critical Care, 11, (4), pp. 151-152. (doi:10.1186/cc5921).

Record type: Article

Abstract

Caudwell Xtreme Everest (CXE) is a large healthy volunteer field study investigating human adaptation to environmental hypoxia. More than 200 individuals were studied at sea-level and in four laboratories on the trek to Everest Base Camp (5,300 m). Fifteen physicians climbed high on Everest and continued the studies as they ascended; eight of these individuals reached the summit of Everest and succeeded in sampling arterial blood at 8,400 m on their descent. Core measurements included cardiopulmonary exercise testing, neuropsychological assessment, near infra-red spectroscopy of brain and exercising muscle, blood markers and daily recording of simple physiological variables. The goal of CXE is to further our understanding of human adaptation to cellular hypoxia, a fundamental mechanism of injury in critical illness, with the aim of improving the care of critically ill patients.

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Published date: 1 August 2007
Organisations: Human Development & Health

Identifiers

Local EPrints ID: 348943
URI: http://eprints.soton.ac.uk/id/eprint/348943
ISSN: 1364-8535
PURE UUID: 5f9cf254-cf78-4903-9dfa-52e5115844bd

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Date deposited: 04 Mar 2013 14:20
Last modified: 18 Jul 2017 04:46

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Contributors

Author: Mike Grocott
Author: Alan Richardson
Author: Hugh Montgomery
Author: Monty Mythen

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