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Perioperative fluid management and clinical outcomes in adults

Perioperative fluid management and clinical outcomes in adults
Perioperative fluid management and clinical outcomes in adults
The administration of IV fluid to avoid dehydration, maintain an effective circulating volume, and prevent inadequate tissue perfusion should be considered, along with the maintenance of sleep, pain relief, and muscular relaxation, a core element of the perioperative practice of anesthesia. Knowledge of the effects of different fluids has increased in recent years, and the choice of fluid type in a variety of clinical situations can now be rationally guided by an understanding of the physicochemical and biological properties of the various crystalloid and colloid solutions available. However, there are few useful clinical outcome data to guide this decision. Deciding how much fluid to give has historically been more controversial than choosing which fluid to use. A number of clinical studies support the notion that an approach based on administering fluids to achieve maximal left ventricular stroke volume (while avoiding excess fluid administration and consequent impairment of left ventricular performance) may improve outcomes. In this article, we review the available fluid types and strategies of fluid administration and discuss their relationship to clinical outcomes in adults.
0003-2999
1093-1106
Grocott, Michael P.W.
1e87b741-513e-4a22-be13-0f7bb344e8c2
Mythen, Michael G.
940f5be7-e5bc-4a90-94aa-09fdc658caad
Gan, Tong J.
3e877034-bb19-43e2-8dba-1d26059de9ec
Grocott, Michael P.W.
1e87b741-513e-4a22-be13-0f7bb344e8c2
Mythen, Michael G.
940f5be7-e5bc-4a90-94aa-09fdc658caad
Gan, Tong J.
3e877034-bb19-43e2-8dba-1d26059de9ec

Grocott, Michael P.W., Mythen, Michael G. and Gan, Tong J. (2005) Perioperative fluid management and clinical outcomes in adults. Anesthesia & Analgesia, 100 (4), 1093-1106. (doi:10.1213/01.ANE.0000148691.33690.AC). (PMID:15781528)

Record type: Article

Abstract

The administration of IV fluid to avoid dehydration, maintain an effective circulating volume, and prevent inadequate tissue perfusion should be considered, along with the maintenance of sleep, pain relief, and muscular relaxation, a core element of the perioperative practice of anesthesia. Knowledge of the effects of different fluids has increased in recent years, and the choice of fluid type in a variety of clinical situations can now be rationally guided by an understanding of the physicochemical and biological properties of the various crystalloid and colloid solutions available. However, there are few useful clinical outcome data to guide this decision. Deciding how much fluid to give has historically been more controversial than choosing which fluid to use. A number of clinical studies support the notion that an approach based on administering fluids to achieve maximal left ventricular stroke volume (while avoiding excess fluid administration and consequent impairment of left ventricular performance) may improve outcomes. In this article, we review the available fluid types and strategies of fluid administration and discuss their relationship to clinical outcomes in adults.

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Published date: April 2005
Organisations: Human Development & Health

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Local EPrints ID: 348957
URI: http://eprints.soton.ac.uk/id/eprint/348957
ISSN: 0003-2999
PURE UUID: 139d9196-d879-48e9-85dd-4eeb86ae1841
ORCID for Michael P.W. Grocott: ORCID iD orcid.org/0000-0002-9484-7581

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Date deposited: 04 Mar 2013 16:06
Last modified: 15 Mar 2024 03:33

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Contributors

Author: Michael G. Mythen
Author: Tong J. Gan

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