Understanding gastrointestinal perfusion in critical care: so near, and yet so far
Understanding gastrointestinal perfusion in critical care: so near, and yet so far
An association between abnormal gastrointestinal perfusion and critical illness has been suggested for a number of years. Much of the data to support this idea comes from studies using gastric tonometry. Although an attractive technology, the interpretation of tonometry data is complex. Furthermore, current understanding of the physiology of gastrointestinal perfusion in health and disease is incomplete. This review considers critically the striking clinical data and basic physiological investigations that support a key role for gastrointestinal hypoperfusion in initiating and/or perpetuating critical disease.
gastric tonometry, sepsis, shock, splanchnic circulation
269-281
Ackland, Gareth
bb1ef7dd-0a25-4c8c-9963-9b216115468d
Grocott, Michael P.W.
1e87b741-513e-4a22-be13-0f7bb344e8c2
Mythen, Michael G.
940f5be7-e5bc-4a90-94aa-09fdc658caad
2000
Ackland, Gareth
bb1ef7dd-0a25-4c8c-9963-9b216115468d
Grocott, Michael P.W.
1e87b741-513e-4a22-be13-0f7bb344e8c2
Mythen, Michael G.
940f5be7-e5bc-4a90-94aa-09fdc658caad
Ackland, Gareth, Grocott, Michael P.W. and Mythen, Michael G.
(2000)
Understanding gastrointestinal perfusion in critical care: so near, and yet so far.
Critical Care, 4 (5), .
(doi:10.1186/cc709).
(PMID:11094506)
Abstract
An association between abnormal gastrointestinal perfusion and critical illness has been suggested for a number of years. Much of the data to support this idea comes from studies using gastric tonometry. Although an attractive technology, the interpretation of tonometry data is complex. Furthermore, current understanding of the physiology of gastrointestinal perfusion in health and disease is incomplete. This review considers critically the striking clinical data and basic physiological investigations that support a key role for gastrointestinal hypoperfusion in initiating and/or perpetuating critical disease.
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Published date: 2000
Keywords:
gastric tonometry, sepsis, shock, splanchnic circulation
Organisations:
Human Development & Health
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Local EPrints ID: 348976
URI: http://eprints.soton.ac.uk/id/eprint/348976
ISSN: 1364-8535
PURE UUID: a29fdaa7-568f-4890-a2bc-1cd1affb1a6a
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Date deposited: 27 Feb 2013 11:07
Last modified: 15 Mar 2024 03:33
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Author:
Gareth Ackland
Author:
Michael G. Mythen
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