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Understanding gastrointestinal perfusion in critical care: so near, and yet so far

Ackland, Gareth, Grocott, Michael P.W. and Mythen, Michael G. (2000) Understanding gastrointestinal perfusion in critical care: so near, and yet so far Critical Care, 4, (5), pp. 269-281. (doi:10.1186/cc709). (PMID:11094506).

Record type: Article


An association between abnormal gastrointestinal perfusion and critical illness has been suggested for a number of years. Much of the data to support this idea comes from studies using gastric tonometry. Although an attractive technology, the interpretation of tonometry data is complex. Furthermore, current understanding of the physiology of gastrointestinal perfusion in health and disease is incomplete. This review considers critically the striking clinical data and basic physiological investigations that support a key role for gastrointestinal hypoperfusion in initiating and/or perpetuating critical disease.

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Published date: 2000
Keywords: gastric tonometry, sepsis, shock, splanchnic circulation
Organisations: Human Development & Health


Local EPrints ID: 348976
ISSN: 1364-8535
PURE UUID: a29fdaa7-568f-4890-a2bc-1cd1affb1a6a

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Date deposited: 27 Feb 2013 11:07
Last modified: 18 Jul 2017 04:46

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Author: Gareth Ackland
Author: Michael G. Mythen

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