Understanding gastrointestinal perfusion in critical care: so near, and yet so far


Ackland, Gareth, Grocott, Michael P.W. and Mythen, Michael G. (2000) Understanding gastrointestinal perfusion in critical care: so near, and yet so far Critical Care, 4, (5), pp. 269-281. (doi:10.1186/cc709). (PMID:11094506).

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Description/Abstract

An association between abnormal gastrointestinal perfusion and critical illness has been suggested for a number of years. Much of the data to support this idea comes from studies using gastric tonometry. Although an attractive technology, the interpretation of tonometry data is complex. Furthermore, current understanding of the physiology of gastrointestinal perfusion in health and disease is incomplete. This review considers critically the striking clinical data and basic physiological investigations that support a key role for gastrointestinal hypoperfusion in initiating and/or perpetuating critical disease.

Item Type: Article
Digital Object Identifier (DOI): doi:10.1186/cc709
ISSNs: 1364-8535 (print)
Keywords: gastric tonometry, sepsis, shock, splanchnic circulation
Subjects: Q Science > QP Physiology
R Medicine > RC Internal medicine
Organisations: Human Development & Health
ePrint ID: 348976
Date :
Date Event
2000Published
Date Deposited: 27 Feb 2013 11:07
Last Modified: 17 Apr 2017 15:58
Further Information:Google Scholar
URI: http://eprints.soton.ac.uk/id/eprint/348976

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