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Studies of the cavitational effects of clinical ultrasound by sonoluminescence: 4. The effect of therapeutic ultrasound on cells in monolayer culture in a standing wave field

Studies of the cavitational effects of clinical ultrasound by sonoluminescence: 4. The effect of therapeutic ultrasound on cells in monolayer culture in a standing wave field
Studies of the cavitational effects of clinical ultrasound by sonoluminescence: 4. The effect of therapeutic ultrasound on cells in monolayer culture in a standing wave field
In previous work the phenomenon of sonoluminescence (SL) has been used to find the conditions in which transient cavitation during exposure to ultrasound is likely to be maximum. This paper reports the effect of therapeutic ultrasound on growth of mouse tumour cells in monolayer culture when the cells are insonated either at a pressure antinode or at a pressure node in a standing wave ultrasound field that is known to produce strong bands of SL at the pressure antinodes. Reduced cell numbers 72 h after insonation were recorded when the cells were insonated at an antinode but not when they were at a node. The possibility that this effect might be an artefact of the experimental system, and further experiments that could elucidate the nature of the damage, are discussed
1553-1560
Pickworth, M.J.W.
8a0e0f89-fb53-4538-abb8-507923eeaf08
Dendy, P.P.
ee1144be-8597-4abb-b01d-54470a991ba1
Twentyman, P.R.
0ffbeb34-0302-41e3-80d3-c4875a62c460
Leighton, T.G.
3e5262ce-1d7d-42eb-b013-fcc5c286bbae
Pickworth, M.J.W.
8a0e0f89-fb53-4538-abb8-507923eeaf08
Dendy, P.P.
ee1144be-8597-4abb-b01d-54470a991ba1
Twentyman, P.R.
0ffbeb34-0302-41e3-80d3-c4875a62c460
Leighton, T.G.
3e5262ce-1d7d-42eb-b013-fcc5c286bbae

Pickworth, M.J.W., Dendy, P.P., Twentyman, P.R. and Leighton, T.G. (1989) Studies of the cavitational effects of clinical ultrasound by sonoluminescence: 4. The effect of therapeutic ultrasound on cells in monolayer culture in a standing wave field. Physics in Medicine and Biology, 34 (11), 1553-1560.

Record type: Article

Abstract

In previous work the phenomenon of sonoluminescence (SL) has been used to find the conditions in which transient cavitation during exposure to ultrasound is likely to be maximum. This paper reports the effect of therapeutic ultrasound on growth of mouse tumour cells in monolayer culture when the cells are insonated either at a pressure antinode or at a pressure node in a standing wave ultrasound field that is known to produce strong bands of SL at the pressure antinodes. Reduced cell numbers 72 h after insonation were recorded when the cells were insonated at an antinode but not when they were at a node. The possibility that this effect might be an artefact of the experimental system, and further experiments that could elucidate the nature of the damage, are discussed

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Published date: 1989
Organisations: Acoustics Group

Identifiers

Local EPrints ID: 349510
URI: https://eprints.soton.ac.uk/id/eprint/349510
PURE UUID: 37d92e5e-9000-4a70-a445-10e092ab5eda
ORCID for T.G. Leighton: ORCID iD orcid.org/0000-0002-1649-8750

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Date deposited: 06 Mar 2013 14:33
Last modified: 06 Jun 2018 13:08

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