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Studies of the cavitational effects of clinical ultrasound by sonoluminescence: 5. Search for sonoluminescence in vivo in the human cheek

Studies of the cavitational effects of clinical ultrasound by sonoluminescence: 5. Search for sonoluminescence in vivo in the human cheek
Studies of the cavitational effects of clinical ultrasound by sonoluminescence: 5. Search for sonoluminescence in vivo in the human cheek
In a previous experiment, sonoluminescence was observed in aerated water, especially at the pressure anti nodes in the standing-wave field of a physiotherapeutic ultrasound device (Therasonic 1030). Mammalian cells in vitro showed growth inhibition when placed at the pressure antinodes but not at adjacent pressure nodes. In the light of these results, we looked for sonoluminescence in vivo when a similar standing-wave field was set up. To detect luminescence, a light guide was held against the inner surface of the human cheek. This would channel any luminescence photons to a cooled, red sensitive photomultiplier which would quantify the light. Direct insonation of the cheek produced no detectable luminescence. Similarly when a water bag was placed against the outer surface of the cheek, and the latter was insonated through the bag, no luminescence was detected. Sonoluminescence from the water bag was, however, detected when the bag was placed against the inner surface of the cheek, showing that absorption of sound by the cheek tissue was not preventing cavitation. Further analysis showed that if cavitation had been occurring in the cheek without detection using the system employed, then the resulting sonoluminescence would have to be at most 0.025 times as intense as that produced by an equivalent volume of aerated water
0041-624X
181-184
Leighton, T.G.
3e5262ce-1d7d-42eb-b013-fcc5c286bbae
Pickworth, M.J.W.
8a0e0f89-fb53-4538-abb8-507923eeaf08
Tudor, J.
69dac70c-3738-4b5e-b3e7-a2a960f9828c
Dendy, P.P.
ee1144be-8597-4abb-b01d-54470a991ba1
Leighton, T.G.
3e5262ce-1d7d-42eb-b013-fcc5c286bbae
Pickworth, M.J.W.
8a0e0f89-fb53-4538-abb8-507923eeaf08
Tudor, J.
69dac70c-3738-4b5e-b3e7-a2a960f9828c
Dendy, P.P.
ee1144be-8597-4abb-b01d-54470a991ba1

Leighton, T.G., Pickworth, M.J.W., Tudor, J. and Dendy, P.P. (1990) Studies of the cavitational effects of clinical ultrasound by sonoluminescence: 5. Search for sonoluminescence in vivo in the human cheek. Ultrasonics, 28 (3), 181-184. (doi:10.1016/0041-624X(90)90083-Z).

Record type: Article

Abstract

In a previous experiment, sonoluminescence was observed in aerated water, especially at the pressure anti nodes in the standing-wave field of a physiotherapeutic ultrasound device (Therasonic 1030). Mammalian cells in vitro showed growth inhibition when placed at the pressure antinodes but not at adjacent pressure nodes. In the light of these results, we looked for sonoluminescence in vivo when a similar standing-wave field was set up. To detect luminescence, a light guide was held against the inner surface of the human cheek. This would channel any luminescence photons to a cooled, red sensitive photomultiplier which would quantify the light. Direct insonation of the cheek produced no detectable luminescence. Similarly when a water bag was placed against the outer surface of the cheek, and the latter was insonated through the bag, no luminescence was detected. Sonoluminescence from the water bag was, however, detected when the bag was placed against the inner surface of the cheek, showing that absorption of sound by the cheek tissue was not preventing cavitation. Further analysis showed that if cavitation had been occurring in the cheek without detection using the system employed, then the resulting sonoluminescence would have to be at most 0.025 times as intense as that produced by an equivalent volume of aerated water

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Published date: May 1990
Organisations: Acoustics Group

Identifiers

Local EPrints ID: 349515
URI: https://eprints.soton.ac.uk/id/eprint/349515
ISSN: 0041-624X
PURE UUID: bf1f5b4d-fa23-4df2-97a7-d76bc6a3ddb4
ORCID for T.G. Leighton: ORCID iD orcid.org/0000-0002-1649-8750

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Date deposited: 06 Mar 2013 14:58
Last modified: 06 Jun 2018 13:08

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