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Treatment of osteoporosis in men

Treatment of osteoporosis in men
Treatment of osteoporosis in men
Summary: Aspects of osteoporosis in men, such as screening and identification strategies, definitions of diagnosis and intervention thresholds, and treatment options (both approved and in the pipeline) are discussed.

Introduction: Awareness of osteoporosis in men is improving, although it remains under-diagnosed and under-treated. A European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) workshop was convened to discuss osteoporosis in men and to provide a report by a panel of experts (the authors).

Methods: A debate with an expert panel on preselected topics was conducted.

Results and conclusions: Although additional fracture data are needed to endorse the clinical care of osteoporosis in men, consensus views were reached on diagnostic criteria and intervention thresholds. Empirical data in men display similarities with data acquired in women, despite pathophysiological differences, which may not be clinically relevant. Men should receive treatment at a similar 10-year fracture probability as in women. The design of mixed studies may reduce the lag between comparable treatments for osteoporosis in women becoming available in men.
8756-3282
134-144
Kaufman, J.M.
b79b47cd-16f0-4619-bf7c-fb77b115d2cd
Reginster, J.Y.
4083b457-5347-4ece-a53e-af19c8868c42
Boonen, S.
19c70ece-493f-4b7c-9bf9-5e4a4a887ba4
Brandi, M.L.
4147f967-9c22-494d-ae35-c8141161413d
Cooper, C.
e05f5612-b493-4273-9b71-9e0ce32bdad6
Dere, W.
e2e72664-566b-4db6-863a-9a62e116849c
Devogelaer, J.P.
d1463836-4c7f-4a2f-b741-c4c7206d838e
Diez-Perez, A.
19f89c53-003a-469c-92ac-69b0b979f3ec
Kanis, J.A.
8da04a36-08a7-4310-b4b4-a6d432439587
McCloskey, E.
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Mitlak, B.
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Orwoll, E.
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Ringe, J.D.
28bfb3bb-3ef5-4d52-8f96-1a05ab813fb5
Weryha, G.
abd87755-4125-492f-a97d-585fb6d3e732
Rizzoli, R.
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Kaufman, J.M.
b79b47cd-16f0-4619-bf7c-fb77b115d2cd
Reginster, J.Y.
4083b457-5347-4ece-a53e-af19c8868c42
Boonen, S.
19c70ece-493f-4b7c-9bf9-5e4a4a887ba4
Brandi, M.L.
4147f967-9c22-494d-ae35-c8141161413d
Cooper, C.
e05f5612-b493-4273-9b71-9e0ce32bdad6
Dere, W.
e2e72664-566b-4db6-863a-9a62e116849c
Devogelaer, J.P.
d1463836-4c7f-4a2f-b741-c4c7206d838e
Diez-Perez, A.
19f89c53-003a-469c-92ac-69b0b979f3ec
Kanis, J.A.
8da04a36-08a7-4310-b4b4-a6d432439587
McCloskey, E.
5211de37-303a-42f8-b24b-00c475264f78
Mitlak, B.
5bd5363a-768e-4e9c-8662-1a54fb6143df
Orwoll, E.
0533e322-dc2b-4460-b2c1-6e9b89e35a3a
Ringe, J.D.
28bfb3bb-3ef5-4d52-8f96-1a05ab813fb5
Weryha, G.
abd87755-4125-492f-a97d-585fb6d3e732
Rizzoli, R.
2214fb77-8fb7-4c0b-bfc4-9f8d3cace5d7

Kaufman, J.M., Reginster, J.Y., Boonen, S., Brandi, M.L., Cooper, C., Dere, W., Devogelaer, J.P., Diez-Perez, A., Kanis, J.A., McCloskey, E., Mitlak, B., Orwoll, E., Ringe, J.D., Weryha, G. and Rizzoli, R. (2013) Treatment of osteoporosis in men. Bone, 53 (1), 134-144. (doi:10.1016/j.bone.2012.11.018). (PMID:23201268)

Record type: Article

Abstract

Summary: Aspects of osteoporosis in men, such as screening and identification strategies, definitions of diagnosis and intervention thresholds, and treatment options (both approved and in the pipeline) are discussed.

Introduction: Awareness of osteoporosis in men is improving, although it remains under-diagnosed and under-treated. A European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) workshop was convened to discuss osteoporosis in men and to provide a report by a panel of experts (the authors).

Methods: A debate with an expert panel on preselected topics was conducted.

Results and conclusions: Although additional fracture data are needed to endorse the clinical care of osteoporosis in men, consensus views were reached on diagnostic criteria and intervention thresholds. Empirical data in men display similarities with data acquired in women, despite pathophysiological differences, which may not be clinically relevant. Men should receive treatment at a similar 10-year fracture probability as in women. The design of mixed studies may reduce the lag between comparable treatments for osteoporosis in women becoming available in men.

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More information

Published date: March 2013
Organisations: Faculty of Health Sciences

Identifiers

Local EPrints ID: 350180
URI: http://eprints.soton.ac.uk/id/eprint/350180
ISSN: 8756-3282
PURE UUID: 37ced50b-215f-4a13-9934-0b147e5e20c4
ORCID for C. Cooper: ORCID iD orcid.org/0000-0003-3510-0709

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Date deposited: 19 Mar 2013 14:38
Last modified: 18 Mar 2024 02:45

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Contributors

Author: J.M. Kaufman
Author: J.Y. Reginster
Author: S. Boonen
Author: M.L. Brandi
Author: C. Cooper ORCID iD
Author: W. Dere
Author: J.P. Devogelaer
Author: A. Diez-Perez
Author: J.A. Kanis
Author: E. McCloskey
Author: B. Mitlak
Author: E. Orwoll
Author: J.D. Ringe
Author: G. Weryha
Author: R. Rizzoli

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