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Survival after liver resection in metastatic colorectal cancer: review and meta-analysis of prognostic factors

Survival after liver resection in metastatic colorectal cancer: review and meta-analysis of prognostic factors
Survival after liver resection in metastatic colorectal cancer: review and meta-analysis of prognostic factors
The overall median survival following CLM liver resection was 3.6 years. All seven investigated prognostic factors showed a modest but significant predictive relationship with survival, and certain prognostic factors may prove useful in determining optimal therapeutic options. Due to the increasing complexity of surgical interventions for CLM and the inclusion of patients with higher disease burdens, future studies should consider the potential for selection and referral bias on survival.
1179-1349
283-301
Kanas, Gena P.
cece0ba4-c326-4f52-b33e-baa5e8a72cda
Taylor, Aliki
250708c9-a401-4ff0-a9d3-37f9fdb550da
Primrose, John N.
d85f3b28-24c6-475f-955b-ec457a3f9185
Langeberg, Wendy J.
62205d2b-8f37-4406-8673-160ce294a8db
Kelsh, Michael A.
2d41ab7b-0e4c-42b7-84a7-45de2cef2b00
Mowat, Fionna S.
c0d33584-4524-4dbb-a4bf-8e1eb7735e77
Alexander, Dominik D.
27ef6b75-0e2e-42f0-97f5-62fe15f48311
Choti, Michael A.
f7278c55-3f0d-4ddf-8564-ff13afd0bb5d
Poston, Graeme
786bec44-049d-4d7a-9ac8-5e8a24e525c3
Kanas, Gena P.
cece0ba4-c326-4f52-b33e-baa5e8a72cda
Taylor, Aliki
250708c9-a401-4ff0-a9d3-37f9fdb550da
Primrose, John N.
d85f3b28-24c6-475f-955b-ec457a3f9185
Langeberg, Wendy J.
62205d2b-8f37-4406-8673-160ce294a8db
Kelsh, Michael A.
2d41ab7b-0e4c-42b7-84a7-45de2cef2b00
Mowat, Fionna S.
c0d33584-4524-4dbb-a4bf-8e1eb7735e77
Alexander, Dominik D.
27ef6b75-0e2e-42f0-97f5-62fe15f48311
Choti, Michael A.
f7278c55-3f0d-4ddf-8564-ff13afd0bb5d
Poston, Graeme
786bec44-049d-4d7a-9ac8-5e8a24e525c3

Kanas, Gena P., Taylor, Aliki, Primrose, John N., Langeberg, Wendy J., Kelsh, Michael A., Mowat, Fionna S., Alexander, Dominik D., Choti, Michael A. and Poston, Graeme (2012) Survival after liver resection in metastatic colorectal cancer: review and meta-analysis of prognostic factors. Clinical Epidemiology, 4 (1), 283-301. (doi:10.2147/CLEP.S34285). (PMID:23152705)

Record type: Article

Abstract

The overall median survival following CLM liver resection was 3.6 years. All seven investigated prognostic factors showed a modest but significant predictive relationship with survival, and certain prognostic factors may prove useful in determining optimal therapeutic options. Due to the increasing complexity of surgical interventions for CLM and the inclusion of patients with higher disease burdens, future studies should consider the potential for selection and referral bias on survival.

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More information

Published date: 7 November 2012
Organisations: Cancer Sciences

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Local EPrints ID: 350701
URI: http://eprints.soton.ac.uk/id/eprint/350701
ISSN: 1179-1349
PURE UUID: 8d150436-48ae-4bb4-9dc4-7639fd277f1c
ORCID for John N. Primrose: ORCID iD orcid.org/0000-0002-2069-7605

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Date deposited: 28 Mar 2013 14:57
Last modified: 15 Mar 2024 02:47

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Contributors

Author: Gena P. Kanas
Author: Aliki Taylor
Author: Wendy J. Langeberg
Author: Michael A. Kelsh
Author: Fionna S. Mowat
Author: Dominik D. Alexander
Author: Michael A. Choti
Author: Graeme Poston

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