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The adaptive immune response to colorectal cancer: from the laboratory to clinical practice

The adaptive immune response to colorectal cancer: from the laboratory to clinical practice
The adaptive immune response to colorectal cancer: from the laboratory to clinical practice
An increasing body of evidence supports that visibility of colorectal cancer to immune attack is substantial and that it limits disease progression. Analysis of the adaptive immune infiltrate in resected colorectal cancer specimens offers prognostic information which is independent of conventionally measured parameters and potentially superior in predictive value.
colorectal cancer, lymphocytes, adaptive immune system, prognosis, risk stratification
0748-7983
889-896
Curtis, N. J.
c66321fd-90f1-48ca-9019-377712a9e318
Primrose, J. N.
d85f3b28-24c6-475f-955b-ec457a3f9185
Thomas, G. J.
2ff54aa9-a766-416b-91ee-cf1c5be74106
Mirnezami, A. H.
b3c7aee7-46a4-404c-bfe3-f72388e0bc94
Ottensmeier, C. H.
42b8a398-baac-4843-a3d6-056225675797
Curtis, N. J.
c66321fd-90f1-48ca-9019-377712a9e318
Primrose, J. N.
d85f3b28-24c6-475f-955b-ec457a3f9185
Thomas, G. J.
2ff54aa9-a766-416b-91ee-cf1c5be74106
Mirnezami, A. H.
b3c7aee7-46a4-404c-bfe3-f72388e0bc94
Ottensmeier, C. H.
42b8a398-baac-4843-a3d6-056225675797

Curtis, N. J., Primrose, J. N., Thomas, G. J., Mirnezami, A. H. and Ottensmeier, C. H. (2012) The adaptive immune response to colorectal cancer: from the laboratory to clinical practice. European Journal of Surgical Oncology, 38 (10), 889-896. (doi:10.1016/j.ejso.2012.05.011). (PMID:22721580)

Record type: Article

Abstract

An increasing body of evidence supports that visibility of colorectal cancer to immune attack is substantial and that it limits disease progression. Analysis of the adaptive immune infiltrate in resected colorectal cancer specimens offers prognostic information which is independent of conventionally measured parameters and potentially superior in predictive value.

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More information

Published date: October 2012
Keywords: colorectal cancer, lymphocytes, adaptive immune system, prognosis, risk stratification
Organisations: Cancer Sciences

Identifiers

Local EPrints ID: 350704
URI: https://eprints.soton.ac.uk/id/eprint/350704
ISSN: 0748-7983
PURE UUID: ae5c2fd9-726b-4c51-98d6-28edce9c7138
ORCID for J. N. Primrose: ORCID iD orcid.org/0000-0002-2069-7605

Catalogue record

Date deposited: 05 Apr 2013 10:37
Last modified: 20 Jul 2019 01:19

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