The University of Southampton
University of Southampton Institutional Repository

Immunotherapy for allergic rhinitis

Immunotherapy for allergic rhinitis
Immunotherapy for allergic rhinitis
Allergic rhinitis (AR) affects more than 20% of the population in the United Kingdom and western Europe and represents a major cause of morbidity that includes interference with usual daily activities and impairment of sleep quality. This guidance prepared by the Standards of Care Committee (SOCC) of the British Society for Allergy and Clinical Immunology (BSACI) is for the management of AR in patients that have failed to achieve adequate relief of symptoms despite treatment with intranasal corticosteroids and/or antihistamines. The guideline is based on evidence and is for use by both adult physicians and paediatricians practising allergy. During the development of these guidelines, all BSACI members were included in the consultation process using a web-based system. Their comments and suggestions were carefully considered by the SOCC. Where evidence was lacking, consensus was reached by the experts on the committee. Included in this guideline are indications and contraindications for immunotherapy, criteria for patient selection, the evidence for short- and long-term efficacy of subcutaneous and sublingual immunotherapy, and discussion on safety and the different modes of immunotherapy including, pre-seasonal and co-seasonal treatments. There are sections on children, allergen standardization, vaccines used in the United Kingdom, oral allergy syndrome, cost effectiveness of immunotherapy and practical considerations of undertaking immunotherapy including recommendations on who should undertake immunotherapy and dosing schedules. Finally, there is discussion on potential biomarkers of response to immunotherapy, the use of component-resolved diagnostics, novel approaches, alternative routes and potential areas for future research.
aeroallergens, allergen, allergic rhinitis, allergen standardization, allergy to animals, allergy to house dust mites, asthma, BSACI, cat allergy, component-resolved diagnostics, cost effectiveness, dosing schedules, grass pollen, guideline, immunotherapy, oral allergy syndrome, perennial rhinitis, pollinosis, ragweed allergy, SAR, seasonal pollen induced rhinitis, subcutaneous immunotherapy, sublingual immunotherapy, tree pollen
0954-7894
1177-1200
Walker, S.M.
13ea3abc-751f-477b-91f0-7ebb3921781d
Durham, S.R.
99964123-7d76-411f-94d6-fbddfb1840c8
Till, S.J.
3a66743d-557a-47df-bc89-5f62c7a57645
Roberts, G.
ea00db4e-84e7-4b39-8273-9b71dbd7e2f3
Corrigan, C.J.
d762d0f0-108f-43ac-8160-ac6b3f0b69f9
Leech, S.C.
1d2a065a-37c8-4ad6-bfbb-1c431a8e9e42
Krishna, M.T.
9bd28040-1482-4a78-8e37-7f22cdfe4220
Rajakulasingham, R.K.
df431a70-c1d2-4f2e-b16d-4845c123ce39
Williams, A.
5906f63e-1283-4a30-9ec1-74d19d61b328
Chantrell, J.
894914bd-891e-4992-8ffa-5cfe4d7930b6
Dixon, L.
6d208aac-e596-4b61-97d4-69f783cf5216
Frew, A.J.
c00e9630-a5f0-44b3-add0-44b68836bbcb
Nasser, S.M.
3c932f67-dfa3-401b-b3a5-313399901643
Walker, S.M.
13ea3abc-751f-477b-91f0-7ebb3921781d
Durham, S.R.
99964123-7d76-411f-94d6-fbddfb1840c8
Till, S.J.
3a66743d-557a-47df-bc89-5f62c7a57645
Roberts, G.
ea00db4e-84e7-4b39-8273-9b71dbd7e2f3
Corrigan, C.J.
d762d0f0-108f-43ac-8160-ac6b3f0b69f9
Leech, S.C.
1d2a065a-37c8-4ad6-bfbb-1c431a8e9e42
Krishna, M.T.
9bd28040-1482-4a78-8e37-7f22cdfe4220
Rajakulasingham, R.K.
df431a70-c1d2-4f2e-b16d-4845c123ce39
Williams, A.
5906f63e-1283-4a30-9ec1-74d19d61b328
Chantrell, J.
894914bd-891e-4992-8ffa-5cfe4d7930b6
Dixon, L.
6d208aac-e596-4b61-97d4-69f783cf5216
Frew, A.J.
c00e9630-a5f0-44b3-add0-44b68836bbcb
Nasser, S.M.
3c932f67-dfa3-401b-b3a5-313399901643

Walker, S.M., Durham, S.R., Till, S.J., Roberts, G., Corrigan, C.J., Leech, S.C., Krishna, M.T., Rajakulasingham, R.K., Williams, A., Chantrell, J., Dixon, L., Frew, A.J. and Nasser, S.M. (2011) Immunotherapy for allergic rhinitis. Clinical & Experimental Allergy, 41 (9), 1177-1200. (doi:10.1111/j.1365-2222.2011.03794.x). (PMID:21848757)

Record type: Article

Abstract

Allergic rhinitis (AR) affects more than 20% of the population in the United Kingdom and western Europe and represents a major cause of morbidity that includes interference with usual daily activities and impairment of sleep quality. This guidance prepared by the Standards of Care Committee (SOCC) of the British Society for Allergy and Clinical Immunology (BSACI) is for the management of AR in patients that have failed to achieve adequate relief of symptoms despite treatment with intranasal corticosteroids and/or antihistamines. The guideline is based on evidence and is for use by both adult physicians and paediatricians practising allergy. During the development of these guidelines, all BSACI members were included in the consultation process using a web-based system. Their comments and suggestions were carefully considered by the SOCC. Where evidence was lacking, consensus was reached by the experts on the committee. Included in this guideline are indications and contraindications for immunotherapy, criteria for patient selection, the evidence for short- and long-term efficacy of subcutaneous and sublingual immunotherapy, and discussion on safety and the different modes of immunotherapy including, pre-seasonal and co-seasonal treatments. There are sections on children, allergen standardization, vaccines used in the United Kingdom, oral allergy syndrome, cost effectiveness of immunotherapy and practical considerations of undertaking immunotherapy including recommendations on who should undertake immunotherapy and dosing schedules. Finally, there is discussion on potential biomarkers of response to immunotherapy, the use of component-resolved diagnostics, novel approaches, alternative routes and potential areas for future research.

This record has no associated files available for download.

More information

e-pub ahead of print date: 17 August 2011
Published date: September 2011
Keywords: aeroallergens, allergen, allergic rhinitis, allergen standardization, allergy to animals, allergy to house dust mites, asthma, BSACI, cat allergy, component-resolved diagnostics, cost effectiveness, dosing schedules, grass pollen, guideline, immunotherapy, oral allergy syndrome, perennial rhinitis, pollinosis, ragweed allergy, SAR, seasonal pollen induced rhinitis, subcutaneous immunotherapy, sublingual immunotherapy, tree pollen
Organisations: Human Development & Health

Identifiers

Local EPrints ID: 351130
URI: http://eprints.soton.ac.uk/id/eprint/351130
ISSN: 0954-7894
PURE UUID: 4844228e-75e9-437b-b500-b485678f24c7
ORCID for G. Roberts: ORCID iD orcid.org/0000-0003-2252-1248

Catalogue record

Date deposited: 17 Apr 2013 10:39
Last modified: 15 Mar 2024 03:22

Export record

Altmetrics

Contributors

Author: S.M. Walker
Author: S.R. Durham
Author: S.J. Till
Author: G. Roberts ORCID iD
Author: C.J. Corrigan
Author: S.C. Leech
Author: M.T. Krishna
Author: R.K. Rajakulasingham
Author: A. Williams
Author: J. Chantrell
Author: L. Dixon
Author: A.J. Frew
Author: S.M. Nasser

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×