The epidemiology of pneumococcal carriage and infections in Malaysia
The epidemiology of pneumococcal carriage and infections in Malaysia
In Malaysia, various aspects of the epidemiology of pneumococcal carriage and disease remain largely unclear due to the lack of supporting data. Although a number of relevant studies have been documented, their individual discrete findings are not sufficient to inform experts on pneumococcal epidemiology at a national level. Therefore, in this review we aim to bring together and systematically evaluate the key information regarding pneumococcal disease epidemiology in Malaysia and provide a comprehensive overview of the data. Major aspects discussed include pneumococcal carriage, disease incidence and prevalence, age factors, invasiveness of pneumococci, serotypes, molecular epidemiology and antibiotic susceptibility. Penicillin resistance is increasingly prevalent and studies suggest that the majority of pneumococcal serotypes causing pneumococcal disease in Malaysia are covered by currently available conjugate vaccines. Continued surveillance is needed to provide a better understanding of pneumococcal epidemiology in Malaysia.
707-719
Le, Cheng-Foh
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Jefferies, Johanna M.C.
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Yusof, Mohd Yasim Mohd
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Sekaran, Shamala Devi
db9a3ce9-a74e-458e-9a25-944a740d6b92
Clarke, Stuart C.
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June 2012
Le, Cheng-Foh
ccf6d131-1ac3-4f64-89c9-984b32f93cfa
Jefferies, Johanna M.C.
9468e292-0b41-412d-9470-944e257c7bcf
Yusof, Mohd Yasim Mohd
a6eec35b-57b9-455e-aad8-e8751a77cd81
Sekaran, Shamala Devi
db9a3ce9-a74e-458e-9a25-944a740d6b92
Clarke, Stuart C.
f7d7f7a2-4b1f-4b36-883a-0f967e73fb17
Le, Cheng-Foh, Jefferies, Johanna M.C., Yusof, Mohd Yasim Mohd, Sekaran, Shamala Devi and Clarke, Stuart C.
(2012)
The epidemiology of pneumococcal carriage and infections in Malaysia.
Expert Review of Anti-Infective Therapy, 10 (6), .
(doi:10.1586/eri.12.54).
(PMID:22734960)
Abstract
In Malaysia, various aspects of the epidemiology of pneumococcal carriage and disease remain largely unclear due to the lack of supporting data. Although a number of relevant studies have been documented, their individual discrete findings are not sufficient to inform experts on pneumococcal epidemiology at a national level. Therefore, in this review we aim to bring together and systematically evaluate the key information regarding pneumococcal disease epidemiology in Malaysia and provide a comprehensive overview of the data. Major aspects discussed include pneumococcal carriage, disease incidence and prevalence, age factors, invasiveness of pneumococci, serotypes, molecular epidemiology and antibiotic susceptibility. Penicillin resistance is increasingly prevalent and studies suggest that the majority of pneumococcal serotypes causing pneumococcal disease in Malaysia are covered by currently available conjugate vaccines. Continued surveillance is needed to provide a better understanding of pneumococcal epidemiology in Malaysia.
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Published date: June 2012
Organisations:
Clinical & Experimental Sciences
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Local EPrints ID: 351258
URI: http://eprints.soton.ac.uk/id/eprint/351258
ISSN: 1744-8336
PURE UUID: fc6ea901-6a67-4e73-a889-21e11f972e70
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Date deposited: 17 Apr 2013 13:27
Last modified: 15 Mar 2024 03:26
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Author:
Cheng-Foh Le
Author:
Johanna M.C. Jefferies
Author:
Mohd Yasim Mohd Yusof
Author:
Shamala Devi Sekaran
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