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Correction of unexpected distributions of P values from analysis of whole genome arrays by rectifying violation of statistical assumptions

Correction of unexpected distributions of P values from analysis of whole genome arrays by rectifying violation of statistical assumptions
Correction of unexpected distributions of P values from analysis of whole genome arrays by rectifying violation of statistical assumptions
The statistical analysis of 'omics data requires careful handling, especially in the choice of statistical test. To obtain meaningful results it is essential that the assumptions behind these tests are carefully examined and any violations rectified where possible, or a more appropriate statistical test chosen.
1471-2164
161
Barton, Sheila J.
4f674382-ca0b-44ad-9670-e71a0b134ef0
Crozier, Sarah R.
f725a749-98a7-47ba-aa6b-8d8e17c72cad
Lillycrop, Karen A.
eeaaa78d-0c4d-4033-a178-60ce7345a2cc
Godfrey, Keith M.
0931701e-fe2c-44b5-8f0d-ec5c7477a6fd
Inskip, Hazel M.
5fb4470a-9379-49b2-a533-9da8e61058b7
Barton, Sheila J.
4f674382-ca0b-44ad-9670-e71a0b134ef0
Crozier, Sarah R.
f725a749-98a7-47ba-aa6b-8d8e17c72cad
Lillycrop, Karen A.
eeaaa78d-0c4d-4033-a178-60ce7345a2cc
Godfrey, Keith M.
0931701e-fe2c-44b5-8f0d-ec5c7477a6fd
Inskip, Hazel M.
5fb4470a-9379-49b2-a533-9da8e61058b7

Barton, Sheila J., Crozier, Sarah R., Lillycrop, Karen A., Godfrey, Keith M. and Inskip, Hazel M. (2013) Correction of unexpected distributions of P values from analysis of whole genome arrays by rectifying violation of statistical assumptions. BMC Genomics, 14, 161. (doi:10.1186/1471-2164-14-161). (PMID:23496791)

Record type: Article

Abstract

The statistical analysis of 'omics data requires careful handling, especially in the choice of statistical test. To obtain meaningful results it is essential that the assumptions behind these tests are carefully examined and any violations rectified where possible, or a more appropriate statistical test chosen.

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Published date: March 2013
Organisations: Faculty of Medicine

Identifiers

Local EPrints ID: 351851
URI: https://eprints.soton.ac.uk/id/eprint/351851
ISSN: 1471-2164
PURE UUID: a1ab1f3b-d6db-4a75-bf5f-e4c68db5fa1a
ORCID for Sheila J. Barton: ORCID iD orcid.org/0000-0003-4963-4242
ORCID for Karen A. Lillycrop: ORCID iD orcid.org/0000-0001-7350-5489
ORCID for Keith M. Godfrey: ORCID iD orcid.org/0000-0002-4643-0618
ORCID for Hazel M. Inskip: ORCID iD orcid.org/0000-0001-8897-1749

Catalogue record

Date deposited: 25 Apr 2013 10:49
Last modified: 20 Jul 2019 01:22

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Contributors

Author: Sarah R. Crozier
Author: Hazel M. Inskip ORCID iD

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