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The innate antiviral response upregulates IL-13 receptor ?2 in bronchial fibroblasts

The innate antiviral response upregulates IL-13 receptor ?2 in bronchial fibroblasts
The innate antiviral response upregulates IL-13 receptor ?2 in bronchial fibroblasts
IFN-? induces IL-13R?2 expression, leading to a consequential suppression of responsiveness to IL-13. These data suggest cross-talk between TH1 and TH2 pathways and point to an immunomodulatory role for IL-13R?2 in human bronchial fibroblasts during viral infection
0091-6749
849-855
Campbell-Harding, Gemma
49a1dc97-d914-4a0f-94d2-406f7844f125
Sawkins, Hannah
ee1416b5-958b-492d-95ba-eb689d810728
Bedke, Nicole
981dbd61-1912-4231-b6d5-42520c38178d
Holgate, Stephen T
2e7c17a9-6796-436e-8772-1fe6d2ac5edc
Davies, Donna E
7de8fdc7-3640-4e3a-aa91-d0e03f990c38
Andrews, Allison-Lynn
4ddaec43-0f43-40cd-a191-aa53b0b30f16
Campbell-Harding, Gemma
49a1dc97-d914-4a0f-94d2-406f7844f125
Sawkins, Hannah
ee1416b5-958b-492d-95ba-eb689d810728
Bedke, Nicole
981dbd61-1912-4231-b6d5-42520c38178d
Holgate, Stephen T
2e7c17a9-6796-436e-8772-1fe6d2ac5edc
Davies, Donna E
7de8fdc7-3640-4e3a-aa91-d0e03f990c38
Andrews, Allison-Lynn
4ddaec43-0f43-40cd-a191-aa53b0b30f16

Campbell-Harding, Gemma, Sawkins, Hannah, Bedke, Nicole, Holgate, Stephen T, Davies, Donna E and Andrews, Allison-Lynn (2013) The innate antiviral response upregulates IL-13 receptor ?2 in bronchial fibroblasts. Journal of Allergy and Clinical Immunology, 131 (3), 849-855. (doi:10.1016/j.jaci.2012.08.030). (PMID:23069489)

Record type: Article

Abstract

IFN-? induces IL-13R?2 expression, leading to a consequential suppression of responsiveness to IL-13. These data suggest cross-talk between TH1 and TH2 pathways and point to an immunomodulatory role for IL-13R?2 in human bronchial fibroblasts during viral infection

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More information

Published date: March 2013
Organisations: Clinical & Experimental Sciences

Identifiers

Local EPrints ID: 352120
URI: http://eprints.soton.ac.uk/id/eprint/352120
DOI: doi:10.1016/j.jaci.2012.08.030
ISSN: 0091-6749
PURE UUID: 15138447-3efa-416c-9aca-ba272984a656
ORCID for Donna E Davies: ORCID iD orcid.org/0000-0002-5117-2991

Catalogue record

Date deposited: 02 May 2013 10:57
Last modified: 15 Mar 2024 02:35

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Contributors

Author: Gemma Campbell-Harding
Author: Hannah Sawkins
Author: Nicole Bedke
Author: Stephen T Holgate
Author: Donna E Davies ORCID iD
Author: Allison-Lynn Andrews

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