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Single molecule SERS and detection of biomolecules with a single gold nanoparticle on mirror junction

Single molecule SERS and detection of biomolecules with a single gold nanoparticle on mirror junction
Single molecule SERS and detection of biomolecules with a single gold nanoparticle on mirror junction
Using the bianalyte method we unambiguously demonstrate that a single gold nanosphere on a metal film junction, in the so-called nanoparticle on a mirror configuration, is capable of single molecule detection with surface-enhanced Raman spectroscopy (SERS). Also this configuration serves as a convenient and highly sensitive SERS sensor for detection of biomolecules. Such simple nano-junction based systems are ideal for chemical and biomedical analysis.
0003-2654
4574-4578
Li, Li
8e6fbabd-aac6-4bb0-a273-a77750dc5b92
Hutter, Tanya
b9494787-9ae0-4887-b4ee-dbe0a0b774b1
Steiner, Ullrich
839dfd85-73db-4125-b9e9-775296f6411f
Mahajan, Sumeet
b131f40a-479e-4432-b662-19d60d4069e9
Li, Li
8e6fbabd-aac6-4bb0-a273-a77750dc5b92
Hutter, Tanya
b9494787-9ae0-4887-b4ee-dbe0a0b774b1
Steiner, Ullrich
839dfd85-73db-4125-b9e9-775296f6411f
Mahajan, Sumeet
b131f40a-479e-4432-b662-19d60d4069e9

Li, Li, Hutter, Tanya, Steiner, Ullrich and Mahajan, Sumeet (2013) Single molecule SERS and detection of biomolecules with a single gold nanoparticle on mirror junction. Analyst, 138, 4574-4578. (doi:10.1039/C3AN00447C).

Record type: Article

Abstract

Using the bianalyte method we unambiguously demonstrate that a single gold nanosphere on a metal film junction, in the so-called nanoparticle on a mirror configuration, is capable of single molecule detection with surface-enhanced Raman spectroscopy (SERS). Also this configuration serves as a convenient and highly sensitive SERS sensor for detection of biomolecules. Such simple nano-junction based systems are ideal for chemical and biomedical analysis.

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Published date: 2 May 2013
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Organisations: Institute for Life Sciences, Molecular Diagnostics & Thereputics
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Identifiers

Local EPrints ID: 352142
URI: http://eprints.soton.ac.uk/id/eprint/352142
DOI: doi:10.1039/C3AN00447C
ISSN: 0003-2654
PURE UUID: 138f4e4e-b34c-4472-bc79-d3f8500a8e4c
ORCID for Sumeet Mahajan: ORCID iD orcid.org/0000-0001-8923-6666

Catalogue record

Date deposited: 07 May 2013 11:00
Last modified: 15 Mar 2024 03:28

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Contributors

Author: Li Li
Author: Tanya Hutter
Author: Ullrich Steiner
Author: Sumeet Mahajan ORCID iD

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