Testing the extent of sequence similarity among viroids, satellite RNAs and hepatitis delta virus
Testing the extent of sequence similarity among viroids, satellite RNAs and hepatitis delta virus
A Monte Carlo method was used to test the extent of sequence similarity among viroids, satellite RNAs, and hepatitis delta virus. This analysis revealed that there is insufficient sequence similarity among these pathogens to support the hypothesis that they have a common evolutionary origin. Furthermore, while definite patterns of sequence similarity were observed among some viroids, there was a clear lack of overall similarity, indicating that a monophyletic origin for even this group cannot be reliably supported from sequence data alone.
viroids, satellite rnas, hepatitis delta virus, Monte Carlo simulation, sequence similarity
98-102
Jenkins, Gareth M.
54ee2d8f-e7a9-4140-8bfd-c9d574789016
Woelk, Christopher H.
4d3af0fd-658f-4626-b3b5-49a6192bcf7d
Rambaut, Andrew
2b7f87ef-95c8-4069-a3db-bca4b38271ec
Holmes, Edward C.
0dab0ee7-07f4-429c-a809-e181fde89b0f
January 2000
Jenkins, Gareth M.
54ee2d8f-e7a9-4140-8bfd-c9d574789016
Woelk, Christopher H.
4d3af0fd-658f-4626-b3b5-49a6192bcf7d
Rambaut, Andrew
2b7f87ef-95c8-4069-a3db-bca4b38271ec
Holmes, Edward C.
0dab0ee7-07f4-429c-a809-e181fde89b0f
Jenkins, Gareth M., Woelk, Christopher H., Rambaut, Andrew and Holmes, Edward C.
(2000)
Testing the extent of sequence similarity among viroids, satellite RNAs and hepatitis delta virus.
Journal of Molecular Evolution, 50 (1), .
(doi:10.1007/s002399910011).
(PMID:10654264)
Abstract
A Monte Carlo method was used to test the extent of sequence similarity among viroids, satellite RNAs, and hepatitis delta virus. This analysis revealed that there is insufficient sequence similarity among these pathogens to support the hypothesis that they have a common evolutionary origin. Furthermore, while definite patterns of sequence similarity were observed among some viroids, there was a clear lack of overall similarity, indicating that a monophyletic origin for even this group cannot be reliably supported from sequence data alone.
This record has no associated files available for download.
More information
Published date: January 2000
Keywords:
viroids, satellite rnas, hepatitis delta virus, Monte Carlo simulation, sequence similarity
Organisations:
Clinical & Experimental Sciences
Identifiers
Local EPrints ID: 352588
URI: http://eprints.soton.ac.uk/id/eprint/352588
ISSN: 0022-2844
PURE UUID: 662f7be3-1b10-40d9-9d6f-300c163c997d
Catalogue record
Date deposited: 21 May 2013 09:30
Last modified: 14 Mar 2024 13:54
Export record
Altmetrics
Contributors
Author:
Gareth M. Jenkins
Author:
Christopher H. Woelk
Author:
Andrew Rambaut
Author:
Edward C. Holmes
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics