The University of Southampton
University of Southampton Institutional Repository

Testing the extent of sequence similarity among viroids, satellite RNAs and hepatitis delta virus

Testing the extent of sequence similarity among viroids, satellite RNAs and hepatitis delta virus
Testing the extent of sequence similarity among viroids, satellite RNAs and hepatitis delta virus
A Monte Carlo method was used to test the extent of sequence similarity among viroids, satellite RNAs, and hepatitis delta virus. This analysis revealed that there is insufficient sequence similarity among these pathogens to support the hypothesis that they have a common evolutionary origin. Furthermore, while definite patterns of sequence similarity were observed among some viroids, there was a clear lack of overall similarity, indicating that a monophyletic origin for even this group cannot be reliably supported from sequence data alone.
viroids, satellite rnas, hepatitis delta virus, Monte Carlo simulation, sequence similarity
0022-2844
98-102
Jenkins, Gareth M.
54ee2d8f-e7a9-4140-8bfd-c9d574789016
Woelk, Christopher H.
4d3af0fd-658f-4626-b3b5-49a6192bcf7d
Rambaut, Andrew
2b7f87ef-95c8-4069-a3db-bca4b38271ec
Holmes, Edward C.
0dab0ee7-07f4-429c-a809-e181fde89b0f
Jenkins, Gareth M.
54ee2d8f-e7a9-4140-8bfd-c9d574789016
Woelk, Christopher H.
4d3af0fd-658f-4626-b3b5-49a6192bcf7d
Rambaut, Andrew
2b7f87ef-95c8-4069-a3db-bca4b38271ec
Holmes, Edward C.
0dab0ee7-07f4-429c-a809-e181fde89b0f

Jenkins, Gareth M., Woelk, Christopher H., Rambaut, Andrew and Holmes, Edward C. (2000) Testing the extent of sequence similarity among viroids, satellite RNAs and hepatitis delta virus. Journal of Molecular Evolution, 50 (1), 98-102. (doi:10.1007/s002399910011). (PMID:10654264)

Record type: Article

Abstract

A Monte Carlo method was used to test the extent of sequence similarity among viroids, satellite RNAs, and hepatitis delta virus. This analysis revealed that there is insufficient sequence similarity among these pathogens to support the hypothesis that they have a common evolutionary origin. Furthermore, while definite patterns of sequence similarity were observed among some viroids, there was a clear lack of overall similarity, indicating that a monophyletic origin for even this group cannot be reliably supported from sequence data alone.

Full text not available from this repository.

More information

Published date: January 2000
Keywords: viroids, satellite rnas, hepatitis delta virus, Monte Carlo simulation, sequence similarity
Organisations: Clinical & Experimental Sciences

Identifiers

Local EPrints ID: 352588
URI: https://eprints.soton.ac.uk/id/eprint/352588
ISSN: 0022-2844
PURE UUID: 662f7be3-1b10-40d9-9d6f-300c163c997d

Catalogue record

Date deposited: 21 May 2013 09:30
Last modified: 18 Jul 2017 04:12

Export record

Altmetrics

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of https://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×