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Characterization of an antigenically distinct porcine rotavirus

Characterization of an antigenically distinct porcine rotavirus
Characterization of an antigenically distinct porcine rotavirus
A porcine virus with rotavirus morphology, which was antigenically unrelated to previously described rotaviruses, is described. Particles with an outer capsid layer measured 75 nm and those lacking the outer layer were 63 nm in diameter. Particles which resembled cores were also identified. The virus was shown to be antigenically distinct from other rotaviruses as judged by immunofluorescence and immune electron microscopy, and it failed to protect piglets from challenge with porcine rotavirus. Analysis of the genome indicated that it was composed of 11 segments of double-stranded RNA with the same overall size range as other rotaviruses but with an unusual segment pattern.
0019-9567
1058-1062
Bridger, Janice C.
4660b463-c316-4cbb-846a-37c7d64f1cda
Clarke, Ian N.
ff6c9324-3547-4039-bb2c-10c0b3327a8b
McCrae, Malcolm A.
f99d4d28-2d4a-4f6a-859f-cebe5df27a94
Bridger, Janice C.
4660b463-c316-4cbb-846a-37c7d64f1cda
Clarke, Ian N.
ff6c9324-3547-4039-bb2c-10c0b3327a8b
McCrae, Malcolm A.
f99d4d28-2d4a-4f6a-859f-cebe5df27a94

Bridger, Janice C., Clarke, Ian N. and McCrae, Malcolm A. (1982) Characterization of an antigenically distinct porcine rotavirus. Infection and Immunity, 35 (3), 1058-1062. (PMID:6175575)

Record type: Article

Abstract

A porcine virus with rotavirus morphology, which was antigenically unrelated to previously described rotaviruses, is described. Particles with an outer capsid layer measured 75 nm and those lacking the outer layer were 63 nm in diameter. Particles which resembled cores were also identified. The virus was shown to be antigenically distinct from other rotaviruses as judged by immunofluorescence and immune electron microscopy, and it failed to protect piglets from challenge with porcine rotavirus. Analysis of the genome indicated that it was composed of 11 segments of double-stranded RNA with the same overall size range as other rotaviruses but with an unusual segment pattern.

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More information

Published date: March 1982
Organisations: Faculty of Medicine

Identifiers

Local EPrints ID: 352619
URI: https://eprints.soton.ac.uk/id/eprint/352619
ISSN: 0019-9567
PURE UUID: d0b5f654-c8f3-4731-bd9c-423a281872cc
ORCID for Ian N. Clarke: ORCID iD orcid.org/0000-0002-4938-1620

Catalogue record

Date deposited: 22 May 2013 11:43
Last modified: 06 Jun 2018 13:19

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Contributors

Author: Janice C. Bridger
Author: Ian N. Clarke ORCID iD
Author: Malcolm A. McCrae

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