Glycerol production by Candida krusei employing NaCl as an osmoregulator in batch and continuous fermentations
Glycerol production by Candida krusei employing NaCl as an osmoregulator in batch and continuous fermentations
Addition of 40 g NaCl l?1 to a chemically defined medium containing 140 g glucose l?1 in shake-flask culture improved glycerol production by Candida krusei from 16.5 g l?1 to 47.7 g l?1. With 40 g NaCl l?1 at a dilution rate of 0.065 h?1, glycerol concentration, glycerol yield (based on glucose consumed), and productivity in a four-stage cascade bioreactor were higher by 240%, 27% and 28%, respectively, than in a single-stage continuous culture system.
candida krusei, glycerol, multistage cascade bioreactor, NaCl, osmoregulator
1137-1140
Liu, Yongqiang
75adc6f8-aa83-484e-9e87-6c8442e344fa
Liu, Dehua
2f9ded17-8371-46cf-98f1-803c92360d06
Su, Qiong
462fab98-be91-49c0-a37c-22d35736cc9b
Xie, Dongming
9d651a52-0d08-4936-9746-128aa52c9b63
2002
Liu, Yongqiang
75adc6f8-aa83-484e-9e87-6c8442e344fa
Liu, Dehua
2f9ded17-8371-46cf-98f1-803c92360d06
Su, Qiong
462fab98-be91-49c0-a37c-22d35736cc9b
Xie, Dongming
9d651a52-0d08-4936-9746-128aa52c9b63
Liu, Yongqiang, Liu, Dehua, Su, Qiong and Xie, Dongming
(2002)
Glycerol production by Candida krusei employing NaCl as an osmoregulator in batch and continuous fermentations.
Biotechnology Letters, 24 (14), .
(doi:10.1023/A:1016170600048).
Abstract
Addition of 40 g NaCl l?1 to a chemically defined medium containing 140 g glucose l?1 in shake-flask culture improved glycerol production by Candida krusei from 16.5 g l?1 to 47.7 g l?1. With 40 g NaCl l?1 at a dilution rate of 0.065 h?1, glycerol concentration, glycerol yield (based on glucose consumed), and productivity in a four-stage cascade bioreactor were higher by 240%, 27% and 28%, respectively, than in a single-stage continuous culture system.
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Published date: 2002
Keywords:
candida krusei, glycerol, multistage cascade bioreactor, NaCl, osmoregulator
Organisations:
Water & Environmental Engineering Group
Identifiers
Local EPrints ID: 352843
URI: http://eprints.soton.ac.uk/id/eprint/352843
ISSN: 0141-5492
PURE UUID: df6c3688-4c20-4da6-8e8f-e726970dacb1
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Date deposited: 17 Jun 2013 14:25
Last modified: 15 Mar 2024 03:47
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Author:
Dehua Liu
Author:
Qiong Su
Author:
Dongming Xie
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