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Glycerol production by Candida krusei employing NaCl as an osmoregulator in batch and continuous fermentations

Glycerol production by Candida krusei employing NaCl as an osmoregulator in batch and continuous fermentations
Glycerol production by Candida krusei employing NaCl as an osmoregulator in batch and continuous fermentations
Addition of 40 g NaCl l?1 to a chemically defined medium containing 140 g glucose l?1 in shake-flask culture improved glycerol production by Candida krusei from 16.5 g l?1 to 47.7 g l?1. With 40 g NaCl l?1 at a dilution rate of 0.065 h?1, glycerol concentration, glycerol yield (based on glucose consumed), and productivity in a four-stage cascade bioreactor were higher by 240%, 27% and 28%, respectively, than in a single-stage continuous culture system.
candida krusei, glycerol, multistage cascade bioreactor, NaCl, osmoregulator
0141-5492
1137-1140
Liu, Yongqiang
75adc6f8-aa83-484e-9e87-6c8442e344fa
Liu, Dehua
2f9ded17-8371-46cf-98f1-803c92360d06
Su, Qiong
462fab98-be91-49c0-a37c-22d35736cc9b
Xie, Dongming
9d651a52-0d08-4936-9746-128aa52c9b63
Liu, Yongqiang
75adc6f8-aa83-484e-9e87-6c8442e344fa
Liu, Dehua
2f9ded17-8371-46cf-98f1-803c92360d06
Su, Qiong
462fab98-be91-49c0-a37c-22d35736cc9b
Xie, Dongming
9d651a52-0d08-4936-9746-128aa52c9b63

Liu, Yongqiang, Liu, Dehua, Su, Qiong and Xie, Dongming (2002) Glycerol production by Candida krusei employing NaCl as an osmoregulator in batch and continuous fermentations. Biotechnology Letters, 24 (14), 1137-1140. (doi:10.1023/A:1016170600048).

Record type: Article

Abstract

Addition of 40 g NaCl l?1 to a chemically defined medium containing 140 g glucose l?1 in shake-flask culture improved glycerol production by Candida krusei from 16.5 g l?1 to 47.7 g l?1. With 40 g NaCl l?1 at a dilution rate of 0.065 h?1, glycerol concentration, glycerol yield (based on glucose consumed), and productivity in a four-stage cascade bioreactor were higher by 240%, 27% and 28%, respectively, than in a single-stage continuous culture system.

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More information

Published date: 2002
Keywords: candida krusei, glycerol, multistage cascade bioreactor, NaCl, osmoregulator
Organisations: Water & Environmental Engineering Group

Identifiers

Local EPrints ID: 352843
URI: http://eprints.soton.ac.uk/id/eprint/352843
ISSN: 0141-5492
PURE UUID: df6c3688-4c20-4da6-8e8f-e726970dacb1
ORCID for Yongqiang Liu: ORCID iD orcid.org/0000-0001-9688-1786

Catalogue record

Date deposited: 17 Jun 2013 14:25
Last modified: 15 Mar 2024 03:47

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Contributors

Author: Yongqiang Liu ORCID iD
Author: Dehua Liu
Author: Qiong Su
Author: Dongming Xie

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