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Epidemiology and burden of osteoarthritis

Epidemiology and burden of osteoarthritis
Epidemiology and burden of osteoarthritis
Background Osteoarthritis (OA) is a degenerative joint disease involving the cartilage and many of its surrounding tissues. Disease progression is usually slow but can ultimately lead to joint failure with pain and disability. OA of the hips and knees tends to cause the greatest burden to the population as pain and stiffness in these large weight-bearing joints often leads to significant disability requiring surgical intervention. Sources of data The article reviews the existing data on epidemiology of osteoarthritis and the burden of the disease. Areas of agreement Symptoms and radiographic changes are poorly correlated in OA. Established risk factors include obesity, local trauma and occupation. The burden of OA is physical, psychological and socioeconomic. Areas of controversy Available data does not allow definite conclusion regarding the roles of nutrition, smoking and sarcopenia as risk factors for developing OA. Growing points Variable methods of diagnosing osteoarthritis have significantly influenced the comparability of the available literature. Areas timely for developing research Further research is required to fully understand how OA affects an individual physically and psychologically, and to determine their healthcare need.
epidemiology, osteoarthritis, burden
0007-1420
185-199
Litwic, Anna
420510aa-23c8-4134-8615-31a85021ae4b
Edwards, Mark H.
b81ff294-1d16-4a1b-af14-9374c5989d4c
Dennison, Elaine M.
ee647287-edb4-4392-8361-e59fd505b1d1
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Litwic, Anna
420510aa-23c8-4134-8615-31a85021ae4b
Edwards, Mark H.
b81ff294-1d16-4a1b-af14-9374c5989d4c
Dennison, Elaine M.
ee647287-edb4-4392-8361-e59fd505b1d1
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6

Litwic, Anna, Edwards, Mark H., Dennison, Elaine M. and Cooper, Cyrus (2013) Epidemiology and burden of osteoarthritis. British Medical Bulletin, 105 (1), 185-199. (doi:10.1093/bmb/lds038). (PMID:23337796)

Record type: Article

Abstract

Background Osteoarthritis (OA) is a degenerative joint disease involving the cartilage and many of its surrounding tissues. Disease progression is usually slow but can ultimately lead to joint failure with pain and disability. OA of the hips and knees tends to cause the greatest burden to the population as pain and stiffness in these large weight-bearing joints often leads to significant disability requiring surgical intervention. Sources of data The article reviews the existing data on epidemiology of osteoarthritis and the burden of the disease. Areas of agreement Symptoms and radiographic changes are poorly correlated in OA. Established risk factors include obesity, local trauma and occupation. The burden of OA is physical, psychological and socioeconomic. Areas of controversy Available data does not allow definite conclusion regarding the roles of nutrition, smoking and sarcopenia as risk factors for developing OA. Growing points Variable methods of diagnosing osteoarthritis have significantly influenced the comparability of the available literature. Areas timely for developing research Further research is required to fully understand how OA affects an individual physically and psychologically, and to determine their healthcare need.

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More information

e-pub ahead of print date: 20 January 2013
Published date: March 2013
Keywords: epidemiology, osteoarthritis, burden
Organisations: Faculty of Medicine

Identifiers

Local EPrints ID: 352937
URI: http://eprints.soton.ac.uk/id/eprint/352937
ISSN: 0007-1420
PURE UUID: 29e51ec6-77b8-4fba-aae6-36f2ee4e1b09
ORCID for Elaine M. Dennison: ORCID iD orcid.org/0000-0002-3048-4961
ORCID for Cyrus Cooper: ORCID iD orcid.org/0000-0003-3510-0709

Catalogue record

Date deposited: 22 May 2013 10:10
Last modified: 18 Feb 2021 16:48

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Contributors

Author: Anna Litwic
Author: Mark H. Edwards
Author: Cyrus Cooper ORCID iD

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