Sensing H+ with conventional neural probes
Sensing H+ with conventional neural probes
In this paper, we demonstrate a technique for transforming commercially available neural probes used for electrical recordings, into chemical sensing devices for detection of ionic concentrations in electrolytes, with particular emphasis to pH. This transformation requires a single post-processing step to incorporate a thin indium tin oxide membrane for sensing H+. Measured results indicate a chemical sensitivity of 28?mV/pH, and relatively low leakage currents (2–10?nA) and drifts (1–10?mV/h). The proposed sensing device demonstrates the possibility of a low-cost implementation that can be reusable and thus versatile, with potential applications in real-time extracellular but mainly intracellular chemical monitoring
223506-[4pp]
Trantidou, T.
1a2705ad-366d-432b-be5f-523d1303930c
Prodromakis, T.
d58c9c10-9d25-4d22-b155-06c8437acfbf
Tsiligkiridis, V.
b43b4058-92b5-4e8c-ab8b-31d38196ab91
Chang, Y.C.
ed8e332c-00b3-4281-9893-ac7dc2ecb983
Toumazou, C.
52728165-8fe5-4c54-9fad-e9ccc4423dd6
2013
Trantidou, T.
1a2705ad-366d-432b-be5f-523d1303930c
Prodromakis, T.
d58c9c10-9d25-4d22-b155-06c8437acfbf
Tsiligkiridis, V.
b43b4058-92b5-4e8c-ab8b-31d38196ab91
Chang, Y.C.
ed8e332c-00b3-4281-9893-ac7dc2ecb983
Toumazou, C.
52728165-8fe5-4c54-9fad-e9ccc4423dd6
Trantidou, T., Prodromakis, T., Tsiligkiridis, V., Chang, Y.C. and Toumazou, C.
(2013)
Sensing H+ with conventional neural probes.
Applied Physics Letters, 102 (22), .
(doi:10.1063/1.4809674).
Abstract
In this paper, we demonstrate a technique for transforming commercially available neural probes used for electrical recordings, into chemical sensing devices for detection of ionic concentrations in electrolytes, with particular emphasis to pH. This transformation requires a single post-processing step to incorporate a thin indium tin oxide membrane for sensing H+. Measured results indicate a chemical sensitivity of 28?mV/pH, and relatively low leakage currents (2–10?nA) and drifts (1–10?mV/h). The proposed sensing device demonstrates the possibility of a low-cost implementation that can be reusable and thus versatile, with potential applications in real-time extracellular but mainly intracellular chemical monitoring
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Published date: 2013
Organisations:
Nanoelectronics and Nanotechnology
Identifiers
Local EPrints ID: 353407
URI: http://eprints.soton.ac.uk/id/eprint/353407
ISSN: 0003-6951
PURE UUID: 8bb4c50c-46d6-4aef-989d-74a6ae713db4
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Date deposited: 06 Jun 2013 07:40
Last modified: 18 Feb 2021 17:22
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Contributors
Author:
T. Trantidou
Author:
V. Tsiligkiridis
Author:
Y.C. Chang
Author:
C. Toumazou
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