Predictors of death after Clostridium difficile infection: a report on 128 strain-typed cases from a teaching hospital in the UK
Predictors of death after Clostridium difficile infection: a report on 128 strain-typed cases from a teaching hospital in the UK
We assessed the relationship between strain type, clinical factors, and outcome in 128 patients with Clostridium difficile infection. Strain type was not associated with any outcome measure. On multivariate analysis, ischemic heart disease and hypoalbuminemia predicted death. Metronidazole treatment in severe disease was associated with a higher rate of treatment failure and death.
e77-e81
Wilson, Vhairi
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Cheek, Liz
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Sarta, Giovanni
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Walker-Bone, Karen
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Cubbon, Marc
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Citron, Diane
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Gerding, Dale N.
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Llewelyn, Martin J.
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15 June 2010
Wilson, Vhairi
f76cac92-5e97-4f66-865c-c0b98418a51a
Cheek, Liz
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Sarta, Giovanni
d449cfd8-928c-47b6-9d38-0a8b20a6e2d7
Walker-Bone, Karen
ad7d1336-ed2c-4f39-ade5-da84eb412109
Cubbon, Marc
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Citron, Diane
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Gerding, Dale N.
abbd3ebd-2c5c-4947-940b-3fc005e54e04
Llewelyn, Martin J.
3e152c2f-2439-444e-9290-2b93b2bf90b8
Wilson, Vhairi, Cheek, Liz, Sarta, Giovanni, Walker-Bone, Karen, Cubbon, Marc, Citron, Diane, Gerding, Dale N. and Llewelyn, Martin J.
(2010)
Predictors of death after Clostridium difficile infection: a report on 128 strain-typed cases from a teaching hospital in the UK.
Clinical Infectious Diseases, 50 (12), .
(doi:10.1086/653012).
(PMID:20450417)
Abstract
We assessed the relationship between strain type, clinical factors, and outcome in 128 patients with Clostridium difficile infection. Strain type was not associated with any outcome measure. On multivariate analysis, ischemic heart disease and hypoalbuminemia predicted death. Metronidazole treatment in severe disease was associated with a higher rate of treatment failure and death.
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e-pub ahead of print date: 7 May 2010
Published date: 15 June 2010
Organisations:
Human Development & Health
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Local EPrints ID: 353521
URI: http://eprints.soton.ac.uk/id/eprint/353521
ISSN: 1058-4838
PURE UUID: 9d649d45-3e4a-4890-a95a-1bd5e0d5ce74
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Date deposited: 10 Jun 2013 13:02
Last modified: 15 Mar 2024 03:04
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Contributors
Author:
Vhairi Wilson
Author:
Liz Cheek
Author:
Giovanni Sarta
Author:
Marc Cubbon
Author:
Diane Citron
Author:
Dale N. Gerding
Author:
Martin J. Llewelyn
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